Jean-Sébastien H.
- Country
- France
- Department
- DMU Cardiovasculaire Renal Transplantation, Centre d'investigations cliniques, CIC 1418
Research Overview
- Evaluation of Balcinrenone and Dapagliflozin on Cardiovascular Outcomes in Heart Failure Patients with Renal Impairment: A Phase III Randomized, Double-Blind Study
- Discontinuation of Beta-Blockers in Heart Failure Patients with Recovered Left Ventricular Ejection Fraction: A Non-Inferiority Study
- BASECOVID - Bevacizumab in post-acute sequelae of COVID-19 : Efficacy and Safety (Pilot Study)
Data & Insights
Has run more than one trial at 14 of 226 partner sites.
Specializations
Cardiovascular Medicine
Specializes in investigating innovative treatments for patients with heart failure, particularly focusing on those with concurrent kidney function impairment.
- Advanced heart failure management
- Cardiovascular outcomes research
- Left ventricular ejection fraction studies
Investigates combination therapies including dapagliflozin and emerging cardiovascular medications.
Therapeutic Optimization
Explores the optimization of beta-blocker therapy in heart failure patients, with particular attention to those who have achieved recovered left ventricular function.
- Medication discontinuation strategies
- Heart failure relapse prevention
- Treatment protocol development
Evaluates therapeutic approaches for both ischemic and non-ischemic heart failure conditions.
Cardiorenal Medicine
Focuses on the intersection of cardiac and renal conditions, investigating treatment strategies for patients with combined cardiovascular and kidney complications.
- Cardiorenal syndrome management
- Multi-organ treatment approaches
- Cardiovascular risk reduction
Studies the effects of novel therapeutic combinations on cardiovascular mortality and hospitalization rates.
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