Jean-Philippe S.
- Country
- France
- Department
- Oncology
Research Overview
- (20289) A Phase 2 Basket Study of the Oral TRK Inhibitor larotrectinib in Subjects with NTRK Fusion-Positive Tumors
- Phase 3 Randomized Study of Carboplatin-Paclitaxel with Retifanlimab vs. Placebo in Inoperable Locally Recurrent or Metastatic Squamous Cell Carcinoma of the Anal Canal
- Phase 2 Randomized Open-Label Study of BDC-1001 Monotherapy and Combination with Pertuzumab in HER2-Positive Metastatic Breast Cancer Post-Trastuzumab Deruxtecan
Data & Insights
Has run more than one trial at 104 of 188 partner sites.
Specializations
Oncology Focus
The investigator specializes in treating advanced solid tumors, with particular emphasis on HER2-expressing cancers and metastatic breast cancer. Their work extends to innovative approaches in treating squamous cell carcinoma and various advanced tumor types.
- HER2-positive metastatic breast cancer
- Advanced solid tumors
- Squamous cell carcinoma of the anal canal
Their expertise includes evaluating novel therapeutic approaches for patients with limited treatment options.
Specialized Treatments
The investigator focuses on developing treatments for cancers with specific genetic markers, including NTRK fusion tumors. They are involved in evaluating both monotherapy approaches and combination therapies with established treatments.
- Targeted therapies for genetic mutations
- Immunotherapy combinations
- Novel therapeutic agents
Their work includes investigating treatments for patients with advanced cancers who have exhausted standard treatment options.
Supportive Care
The investigator addresses important supportive care aspects in cancer treatment, including management of treatment-related complications. Their work encompasses cancer-associated thromboembolism and treatment-induced side effects.
- Cancer-associated venous thromboembolism
- Cisplatin-induced ototoxicity
- Quality of life considerations
Their research includes evaluating preventive strategies for treatment-related adverse effects in cancer patients.
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