Jean Claude S.
- Country
- France
- Department
- Neuroradiologue
Research Overview
Data & Insights
Has run more than one trial at 0 of 1 partner site.
Specializations
Neurovascular and Stroke Interventions
Investigates acute ischemic stroke, large vessel occlusion, and related endovascular strategies, including adjunct thrombolysis and mechanical thrombectomy.
- Acute ischemic stroke
- Basilar artery occlusion
- Endovascular thrombectomy
- Adjunct intra‑arterial thrombolysis
- Ischemic stroke prevention after TIA
Emphasis on functional outcomes and reperfusion success.
Neurodegenerative and Demyelinating Disorders
Explores disease‑modifying approaches for multiple sclerosis, including relapsing and progressive forms, and neuroprotective strategies for Alzheimer's disease.
- Relapsing‑remitting multiple sclerosis
- Primary progressive multiple sclerosis
- Secondary progressive multiple sclerosis
- Alzheimer's disease cognitive preservation
- Neuroinflammation in demyelination
Targets long‑term disability mitigation.
Ophthalmic and Retinal Diseases
Focuses on retinal vascular and degenerative conditions such as neovascular age‑related macular degeneration, diabetic macular edema, and geographic atrophy.
- Neovascular AMD
- Diabetic macular edema
- Geographic atrophy
- Coats' disease
- Fuchs endothelial corneal dystrophy
Integrates visual acuity preservation and retinal thickness monitoring.
Autoimmune and Neuromuscular Disorders
Addresses immune‑mediated disorders including myasthenia gravis, chronic inflammatory demyelinating polyneuropathy, and ocular manifestations of autoimmunity.
- Generalized myasthenia gravis
- Ocular myasthenia gravis
- Chronic inflammatory demyelinating polyneuropathy
- Granulomatosis with polyangiitis
- Behçet’s disease uveitis
Evaluates targeted biologic and immunosuppressive regimens.
Rare Genetic and Metabolic Neurological Conditions
Investigates rare inherited diseases such as Wilson disease and diffuse intrinsic pontine glioma, emphasizing novel gene‑therapy and metabolic modulation.
- Wilson disease copper regulation
- Diffuse intrinsic pontine glioma
- H3K28M mutant gliomas
- Retinoblastoma
- Wilson disease pharmacodynamics
Aims to translate molecular insights into clinical benefit.
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