Jean-Christophe T.
- Country
- France
- Department
- Medical oncology
Research Overview
- Evaluation of Safety and Efficacy of Elacestrant in Combination Therapies for Patients with Metastatic Breast Cancer: A Phase 1b/2 Open-Label Umbrella Study
- ETIC-LM_Multicentric single arm phase II study evaluating the Efficacy of association of Tucatinib, capecitabine and Intra-CSF trastuzumab in HER2 amplified breast cancer patients with Leptomeningeal Metastases.
- Phase III Randomized, Double-Blind Study of Capivasertib and Fulvestrant Versus Placebo and Fulvestrant in HR+/HER2- Advanced or Metastatic Breast Cancer
Data & Insights
Has run more than one trial at 132 of 307 partner sites.
Specializations
Advanced Breast Cancer Specialization
The investigator focuses on treating hormone receptor-positive (HR+) and HER2-negative breast cancer in advanced and metastatic stages. Their research encompasses innovative therapeutic approaches for patients with specific genetic markers.
- Metastatic breast cancer treatment
- HER2-positive leptomeningeal metastases
- Advanced hormone-receptor positive disease
Their work includes evaluation of novel combination therapies targeting specific molecular pathways in breast cancer treatment.
Molecular-Based Cancer Treatments
The investigator specializes in molecular profiling and targeted therapies for various cancer types, with particular attention to genetic alterations and biomarker-driven treatment approaches.
- PIK3CA/AKT1/PTEN alterations
- HRR mutation and HRD positive cancers
- Next-generation sequencing applications
Their research includes evaluation of molecular-based therapeutic strategies in both breast cancer and soft tissue sarcomas.
Innovative Treatment Combinations
The investigator explores novel therapeutic combinations for cancer treatment, focusing on targeted therapies and immunotherapy approaches.
- Combined targeted therapy protocols
- Hormone therapy combinations
- Immunotherapy integration
Their work involves assessment of innovative drug combinations to improve treatment outcomes in advanced cancers.
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