Jean-Baptiste N.
- Country
- France
- Department
- Service d’Explorations Fonctionnelles Neurologiques (EFN)
Research Overview
- Efficacy of Rituximab Versus Placebo in Anti-MAG Neuropathy Patients with Predicted Good Response: A Randomized Controlled Trial
- Phase IIb Evaluation of Ruxolitinib in the Treatment of Inclusion Body Myositis: A Randomized, Double-Blind, Placebo-Controlled Study
- Long-term Safety and Efficacy of Avalglucosidase Alfa in French Patients with Glycogen Storage Disease Type II: A Phase 4 Open-label Extension Study
Data & Insights
Has run more than one trial at 31 of 130 partner sites.
Specializations
Neurology and neuroimmunology
Clinical activity includes peripheral neuropathy, anti-MAG neuropathy, chronic inflammatory demyelinating polyneuropathy, multiple sclerosis, myelin oligodendrocytes glycoprotein antibody-associated disease, and amyotrophic lateral sclerosis, with additional interest in neuropathic pain and spasticity after stroke.
- demyelinating disorders
- peripheral nerve disease
- autoimmune neurological disease
- neurogenic pain syndromes
The therapeutic scope also extends to brainstem glioma, glioblastoma, ependymoma, and medulloblastoma, reflecting involvement in complex central nervous system conditions.
Autoimmune and inflammatory disease
Research interests cover rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, Sjögren's syndrome, vasculitis, polymyalgia rheumatica, and idiopathic inflammatory myopathies, alongside dermatomyositis and polymyositis.
- connective tissue disease
- systemic vasculitis
- inflammatory arthritis
- autoimmune skin disease
Additional therapeutic focus includes mucous membrane pemphigoid, pemphigus, alopecia areata, hidradenitis suppurativa, and atopic dermatitis.
Hematology and cellular therapy
Work spans acute lymphoblastic leukemia, acute myeloid leukemia, myelodysplastic syndrome, myelofibrosis, chronic myeloid leukemia, lymphoma, and multiple myeloma, with attention to both adult and younger populations.
- acute leukemia
- myeloproliferative neoplasm
- lymphoid malignancy
- transplant-related hematology
Therapeutic interests also include allogeneic stem cell transplantation, graft-versus-host disease, immune thrombocytopenia, and hemophilia.
Thoracic, gastrointestinal, and genitourinary oncology
Clinical trials address non-small cell lung cancer, small cell lung cancer, gastric cancer, esophageal cancer, colorectal cancer, pancreatic adenocarcinoma, and hepatocellular carcinoma, with broad involvement across advanced solid tumors.
- lung cancer
- gastroesophageal cancer
- prostate cancer
- urothelial carcinoma
Additional areas include breast cancer, ovarian cancer, endometrial cancer, renal cell carcinoma, and melanoma, with interest in biomarker-driven treatment strategies.
Cardiovascular, renal, and respiratory medicine
Research activity includes atrial fibrillation, stroke prevention, venous thromboembolism, septic shock, cardiomyopathy, and out-of-hospital cardiac arrest, together with broader interest in acute cardiovascular care.
- thromboembolic disease
- heart failure
- chronic kidney disease
- pulmonary hypertension
Additional therapeutic domains include asthma, interstitial lung disease, idiopathic pulmonary fibrosis, bronchiectasis, kidney transplantation, and autosomal dominant polycystic kidney disease.
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