Jarle J.
- Country
- Norway
- Department
- Hjerteseksjonen
Research Overview
- Phase 2b/3 Randomized Double‑Blind Placebo‑Controlled Trial of Ataciguat to Slow Progression and Improve Peak VO2 in Moderate Calcific Aortic Valve Stenosis
- Randomized Comparative Evaluation of Ticagrelor, Prasugrel, and Aspirin/Dipyridamole Combination Therapy for Antiplatelet Management in Acute Coronary Syndrome
- Evaluation of Inclisiran's Efficacy in Reducing Major Adverse Cardiovascular Events in Patients with Atherosclerotic Cardiovascular Disease: A Randomized, Double-Blind, Placebo-Controlled Trial
Data & Insights
Has run more than one trial at 263 of 888 partner sites.
Specializations
Cardiovascular medicine
The investigator is active in clinical research on acute myocardial infarction, atherosclerotic cardiovascular disease, chronic heart failure, stroke, and hypertension, with a clear focus on therapies that reduce ischemic risk and improve long-term cardiovascular outcomes.
- Acute myocardial infarction
- Chronic heart failure
- Atherosclerotic cardiovascular disease
- Stroke
- Hypertension
Additional interests include cardiometabolic risk reduction in type 2 diabetes and the prevention of recurrent cardiovascular events.
Oncology and precision cancer therapy
His trial portfolio includes a broad range of malignant diseases, with emphasis on breast cancer, colorectal cancer, ovarian cancer, prostate cancer, lung cancer, and urothelial cancer, alongside interest in glioblastoma and melanoma.
- Colorectal cancer
- Ovarian cancer
- Prostate cancer
- Non-small cell lung cancer
- Urothelial cancer
He is also involved in studies of targeted therapy, immunotherapy, and precision medicine for advanced and difficult-to-treat cancers.
Neurology and immune-mediated disorders
Clinical research activity extends to multiple sclerosis, amyotrophic lateral sclerosis, chronic migraine, idiopathic painful small fiber neuropathy, and idiopathic sudden sensorineural hearing loss, reflecting involvement in neurological conditions with significant functional impact.
- Multiple sclerosis
- Amyotrophic lateral sclerosis
- Chronic migraine
- Idiopathic painful small fiber neuropathy
- Idiopathic sudden sensorineural hearing loss
He also contributes to research in immune-mediated disease and inflammatory neurological syndromes.
Rheumatology and immunology
The investigator is engaged in therapeutic studies for rheumatoid arthritis, juvenile idiopathic arthritis, antiphospholipid syndrome, immune thrombocytopenia, Behçet’s syndrome, and dermatomyositis.
- Rheumatoid arthritis
- Juvenile idiopathic arthritis
- Immune thrombocytopenia
- Antiphospholipid syndrome
- Dermatomyositis
His research also includes thyroid eye disease, bullous pemphigoid, and other autoimmune diseases requiring targeted immunomodulatory treatment.
Metabolic, endocrine, and supportive care
Additional research interests include primary adrenal insufficiency, type 2 diabetes, cancer-associated cachexia, major depression disorder, and treatment strategies for symptom control and disease maintenance across chronic conditions.
- Primary adrenal insufficiency
- Type 2 diabetes
- Cancer-associated cachexia
- Major depression disorder
- Supportive care in chronic disease
He is also involved in studies addressing infection management and symptom-focused interventions in complex clinical settings.
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