Jan-Willem D. G.
- Country
- The Netherlands
- Department
- 5003; Oncology
Research Overview
- Evaluation of Hepatic Arterial Infusion of Floxuridine with Systemic Therapy in Unresectable Colorectal Liver Metastases: A Randomized Controlled Trial
- Phase 3 Multicenter Trial of Neoadjuvant Ipilimumab and Nivolumab Versus Adjuvant Nivolumab in Patients with Macroscopic Stage III Melanoma
- Efficacy of Adjuvant Hepatic Arterial Infusion of Floxuridine Post-Resection in Low-Risk Resectable Colorectal Liver Metastases: A Randomized Controlled Trial
Data & Insights
Has run more than one trial at 29 of 84 partner sites.
Specializations
Solid Tumor Oncology
Focus on a broad spectrum of solid tumors ranging from thoracic to gastrointestinal and genitourinary malignancies, with emphasis on curative and metastatic disease contexts.
- Non‑Small Cell Lung Cancer
- Breast Cancer
- Renal Cell Carcinoma
- Melanoma
- Pancreatic Cancer
Research activities include adjuvant strategies, targeted therapies, and immuno‑oncology approaches across these disease entities.
Hematologic Malignancies
Dedicated to malignancies of the blood and lymphatic system, addressing both acute and chronic hematologic conditions.
- Acute Myeloid Leukemia
- Chronic Lymphocytic Leukemia
- Multiple Myeloma
- Diffuse Large B‑Cell Lymphoma
- Mantle Cell Lymphoma
Investigations span frontline treatment, maintenance regimens, and novel combination therapies.
Cardiovascular & Thrombotic Disorders
Engaged in the prevention and management of cardiovascular risk and thrombo‑embolic events in diverse patient populations.
- Atherosclerotic Cardiovascular Disease
- Atrial Fibrillation
- Ischemic Stroke
- Venous Thromboembolism
- Peripheral Arterial Disease
Studies address antithrombotic strategies, risk stratification, and outcomes after acute cardiovascular events.
Pulmonary & Respiratory Conditions
Targeting chronic and acute respiratory diseases with a focus on disease control and quality of life.
- Chronic Obstructive Pulmonary Disease
- Asthma
- Bronchiolitis
- Respiratory Distress in Children
- Severe Asthma
Research includes therapeutic optimization, biologic agents, and oxygen‑saturation management protocols.
Renal & Metabolic Disorders
Investigations encompass kidney disease and metabolic abnormalities, often intersecting with oncologic care.
- Chronic Kidney Disease
- Hypertension
- Type 2 Diabetes
- Acute Kidney Injury
- Primary Aldosteronism
Efforts aim to improve renal outcomes, manage comorbid metabolic risk, and integrate supportive care.
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