Jan T.
- Country
- Belgium
- Department
- UZ Leuven Campus Gasthuisberg
Research Overview
- Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Naronapride in Idiopathic or Diabetic Gastroparesis: A Phase 1 Randomized, Single-Blind Study
- Phase 2 Randomized, Double‑Blind, Placebo‑Controlled Study of Brenipatide (LY3537031) for Efficacy and Safety in Adults with Irritable Bowel Syndrome‑Constipation
- Evaluation of Buspirone Hydrochloride on Esophageal Motility and Dysphagia Symptoms in Patients with Ineffective Motility or Absent Peristalsis
Data & Insights
Has run more than one trial at 15 of 84 partner sites.
Specializations
Gastrointestinal Motility Disorders
Specializes in investigating novel treatments for gastroparesis and disorders affecting gastrointestinal movement. Focuses on both idiopathic and diabetic gastroparesis, exploring therapeutic approaches including tradipitant and naronapride.
- Gastroparesis Management
- Esophageal Motility Disorders
- Gastrointestinal Transit Studies
Conducts research on esophageal peristalsis disorders and their treatment using innovative pharmacological approaches.
Reflux and Functional Disorders
Investigates treatments for gastro-esophageal reflux disease and related conditions, including functional heartburn and reflux hypersensitivity. Explores combination therapies with proton pump inhibitors.
- Refractory GERD
- Functional Dyspepsia
- Rumination Syndrome
Studies alternative therapeutic approaches including traditional remedies like Rikkunshito for functional gastrointestinal disorders.
Metabolic and Digestive Conditions
Focuses on post-bariatric hypoglycemia management and digestive disorders. Investigates the relationship between obesity and gastrointestinal motility using advanced imaging techniques.
- Metabolic Complications
- Opioid-Induced Constipation
- Gastrointestinal Hormone Studies
Examines the effects of various medications on gastrointestinal motility and metabolic responses.
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