Jan-Stephan S.
- Country
- The Netherlands
- Department
- Internal Medicine
Research Overview
- A Phase 3 open-label, controlled, randomised, multi-centre trial comparing imlifidase and standard-of-care with standard-of-care alone in the treatment of severe anti-GBM antibody disease (Goodpasture disease)
- Evaluation of Safety and Tolerability of TX200-TR101 in Prophylaxis Against Renal Transplant Rejection in Living Donor Recipients
- Evaluation of Standard Immunosuppression with Tacrolimus and Mycophenolate Mofetil Versus Low-Dose Tacrolimus and Everolimus in Elderly De Novo Renal Transplant Recipients
Data & Insights
Has run more than one trial at 8 of 48 partner sites.
Specializations
Transplant Medicine
This investigator specializes in kidney transplantation and associated therapeutic approaches, with particular focus on preventing and managing transplant rejection. Their research encompasses innovative cell-based therapies, including chimeric antigen receptor T regulatory cell therapy.
- Living donor renal transplantation
- Transplant immunology
- Graft survival optimization
Their work extends to evaluating novel therapeutic strategies for improving transplant outcomes and patient survival rates.
Immunological Disorders
The investigator focuses on complex immunological conditions, particularly anti-GBM antibody disease (Goodpasture disease) and immune system modulation in transplant recipients. Their research includes investigating immunosuppressive therapy optimization.
- Autoimmune kidney diseases
- Immunosuppression management
- Novel immunological therapies
Their expertise includes evaluating immune responses in transplant patients with compromised immunity.
Infectious Disease Management
The investigator studies the intersection of transplant medicine and infectious diseases, with particular attention to COVID-19 and Herpes Zoster in immunocompromised patients. Their work includes optimizing vaccination responses in transplant recipients.
- Vaccine immunogenicity
- Infection prevention strategies
- Immunocompromised patient care
Their research addresses the unique challenges of managing infections in transplant recipients.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.