Jan D. B.
- Country
- Belgium
- Department
- Neurology
Research Overview
- A Phase 2 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of EDG-5506 on Safety, Biomarkers, Pharmacokinetics, and Functional Measures in Adults and Adolescents with Becker Muscular Dystrophy
- Long-term Safety and Biomarker Assessment of EDG-5506 in Adults and Adolescents with Becker Muscular Dystrophy: An Open-Label Extension Study
- A Phase II/III Randomized, Double-blind, Placebo-controlled, Multicenter Study to Determine the Efficacy and Safety of ABC008 in the Treatment of Subjects with Inclusion Body Myositis
Data & Insights
Has run more than one trial at 76 of 162 partner sites.
Specializations
Neuromuscular Disorders
The investigator specializes in treating various forms of myasthenia gravis, including both seropositive and seronegative variants. Their research encompasses novel therapeutic approaches for generalized myasthenia gravis (gMG), focusing on innovative antibody-based treatments.
- Acetylcholine Receptor Antibody Seronegative gMG
- Seropositive Generalized Myasthenia Gravis
Inflammatory Muscle Conditions
The investigator has extensive experience in treating idiopathic inflammatory myopathy (IIM) and inclusion body myositis. Their work involves evaluating both immediate and long-term therapeutic interventions for these challenging muscular conditions.
- Active Idiopathic Inflammatory Myopathy
- Inclusion Body Myositis
- Inflammatory Muscle Disorders
Neurodegenerative Conditions
The investigator focuses on progressive neurological conditions, including amyotrophic lateral sclerosis (ALS) and chronic inflammatory demyelinating polyneuropathy (CIDP). Their research extends to multifocal motor neuropathy and various forms of muscular dystrophy.
- Becker Muscular Dystrophy
- Limb-Girdle Muscular Dystrophy
- Motor Neuron Disease
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