Jamie P.
- Country
- France
- Department
- Pediatrics
Research Overview
- Randomized Phase II/III Study of Cabozantinib Maintenance Versus Best Supportive Care in Osteosarcoma Patients After First‑Line Chemotherapy (FOSTER‑CabOS)
- Evaluation of Regorafenib Addition to VDC/IE Chemotherapy and Maintenance Vinorelbine-Cyclophosphamide in Newly Diagnosed Metastatic Ewing Sarcoma
- Long-term Safety Assessment of Dabrafenib Mesylate and Trametinib in Pediatric Patients with Cancers Harboring V600 Mutation: A Multi-center Roll-over Study
Data & Insights
Has run more than one trial at 38 of 104 partner sites.
Specializations
Pediatric Hematology and Oncology
Jamie Probert is involved in clinical research on childhood cancers and blood disorders, with a strong focus on acute lymphoblastic leukemia, acute myeloid leukemia, and lymphoma care in children and adolescents. The investigator’s activity also extends to solid tumors and high-risk malignant conditions requiring specialized pediatric treatment strategies.
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- Diffuse large B-cell lymphoma
- Neuroblastoma and other pediatric solid tumors
Research activity in this area is linked to pediatric oncology services at Hôpital Pontchaillou-CHU Rennes and Centre Hospitalier Universitaire De Rennes.
Neurodevelopmental and Epilepsy Disorders
The investigator is active in studies addressing epilepsy and complex neurological disorders in children, including syndromic and refractory seizure conditions. This includes interest in developmental and epileptic encephalopathies, focal onset seizures, and inherited neurological disease affecting early life.
- Epilepsy
- Developmental and epileptic encephalopathies
- Focal onset seizures
- Tuberous sclerosis complex-related epilepsy
These interests reflect a therapeutic emphasis on seizure control and neurological outcomes in pediatric populations.
Autoimmune and Inflammatory Disease
Jamie Probert also contributes to research in autoimmune disease and chronic inflammatory conditions, including systemic lupus erythematosus, systemic sclerosis, Crohn's disease, and ulcerative colitis. Additional involvement includes disorders such as hidradenitis suppurativa and sarcoidosis, where immune modulation is central to treatment development.
- Systemic lupus erythematosus
- Systemic sclerosis
- Crohn's disease
- Ulcerative colitis
The investigator’s therapeutic scope includes immune-mediated disease management across pediatric and general hospital settings.
Respiratory and Interstitial Lung Disease
Clinical research activity includes interstitial lung disease, idiopathic pulmonary fibrosis, progressive pulmonary fibrosis, and systemic sclerosis-associated interstitial lung disease. The investigator is also involved in studies related to asthma, bronchiectasis, and other chronic respiratory disorders with significant inflammatory or fibrotic components.
- Interstitial lung disease
- Idiopathic pulmonary fibrosis
- Progressive pulmonary fibrosis
- Systemic sclerosis-associated interstitial lung disease
This area highlights interest in therapies aimed at preserving lung function and limiting fibrotic progression.
Renal, Hepatic, and Transplant-Related Care
The investigator’s research landscape includes kidney disease, renal transplantation, liver disease, and hepatitis-related conditions. Areas of interest also cover hepatic encephalopathy, alpha-1 antitrypsin deficiency-associated liver disease, and post-transplant infectious or immunologic complications.
- Renal transplantation
- Chronic kidney disease
- Hepatic encephalopathy
- Chronic hepatitis B and D
These studies align with therapeutic interests in organ protection, transplant medicine, and chronic multisystem disease management.
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