Jaime S. C. M.
- Country
- Spain
- Department
- Neumology
Research Overview
- A Phase 2a Study to Evaluate the Safety and Efficacy of ABBV-142 in Adults with Idiopathic Pulmonary Fibrosis
- Phase IIb Randomized, Placebo‑Controlled Study of Oral AZD8965 on Forced Vital Capacity in Patients with Idiopathic Pulmonary Fibrosis
- Phase 2 Randomized, Double-Blind, Placebo-Controlled Study on the Efficacy and Safety of MBS2320 in Idiopathic Pulmonary Fibrosis Patients
Data & Insights
Has run more than one trial at 143 of 417 partner sites.
Specializations
Thoracic Oncology
Non-small cell lung cancer, small cell lung cancer, and other advanced thoracic malignancies form a major part of this investigator's clinical research activity, with interest in both unresectable and metastatic disease as well as resectable settings.
- Advanced and metastatic NSCLC
- EGFR-mutated and ALK-positive lung cancer
- ROS1-positive lung cancer
- SCLC and thoracic neuroendocrine neoplasms
Research also extends to biomarker-defined lung cancer subgroups, including molecularly selected and post-treatment populations.
Breast and Gynecologic Malignancies
The investigator is actively involved in studies of breast cancer across early, locally advanced, and metastatic stages, with additional work in ovarian cancer, endometrial cancer, and cervical cancer.
- HR-positive and HER2-negative breast cancer
- HER2-positive and HER2-low breast cancer
- Triple-negative breast cancer
- Platinum-resistant ovarian cancer and recurrent gynecologic tumors
Therapeutic interests include biomarker-driven treatment selection, endocrine-based strategies, and disease control in recurrent gynecologic cancers.
Hematologic Malignancies
Clinical research activity includes a broad range of blood cancers, especially lymphomas, acute leukemias, myelodysplastic syndromes, and myeloproliferative neoplasms.
- Diffuse large B-cell lymphoma and mantle cell lymphoma
- Acute myeloid leukemia and acute lymphoblastic leukemia
- Chronic lymphocytic leukemia and follicular lymphoma
- Multiple myeloma and myelofibrosis
There is also involvement in relapsed or refractory disease and in settings linked to transplant-related care.
Cardiovascular and Metabolic Disease
The investigator's portfolio includes heart failure, acute coronary syndromes, atrial fibrillation, stroke, and broader atherosclerotic cardiovascular disease, together with metabolic risk conditions.
- Heart failure across preserved and reduced ejection fraction phenotypes
- Myocardial infarction and acute ischemic stroke
- Atrial fibrillation and anticoagulation-related care
- Dyslipidemia, obesity, and type 2 diabetes
Research also covers cardiometabolic risk reduction, renal-cardiovascular overlap, and prevention of recurrent vascular events.
Pulmonary, Immune, and Gastrointestinal Disorders
Additional research interests include chronic obstructive pulmonary disease, asthma, pulmonary fibrosis, Crohn's disease, ulcerative colitis, and immune-mediated conditions such as systemic lupus erythematosus and psoriatic arthritis.
- COPD and severe asthma
- Idiopathic pulmonary fibrosis and pulmonary sarcoidosis
- Crohn's disease and ulcerative colitis
- Systemic lupus erythematosus and polymyalgia rheumatica
Therapeutic focus also includes inflammatory disease control, respiratory symptom burden, and immune-mediated organ involvement.
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