Ivan S.
- Country
- Bulgaria
- Department
- N/A
Research Overview
Specializations
Inflammatory Arthritis & Spondyloarthritis
Focuses on immune‑mediated joint disease and axial involvement.
- axial spondyloarthritis
- early axSpA with inadequate NSAID response
- clinical remission endpoints
- objective signs of inflammation
All studies are conducted through the Medical Centre Futuremeds EOOD in Plovdiv.
Inflammatory Bowel Disease
Investigates therapeutic strategies for severe colonic inflammation.
- moderately to severely active Crohn's disease
- moderately to severely active ulcerative colitis
- induction and maintenance therapy
- clinical efficacy of novel biologics
Trials evaluate novel oral and biologic agents for mucosal healing.
Oncologic Immunotherapy & Targeted Therapy
Engages in trials for advanced solid tumours with immune checkpoint modulation.
- non‑small cell lung cancer
- metastatic castration‑sensitive prostate cancer
- KRAS G12C mutation subgroup
- high PD‑L1 expression cohorts
- pembrolizumab combination regimens
Research includes progression‑free and overall survival endpoints.
Metabolic & Cardiovascular Risk Management
Addresses obesity, lipoprotein(a)–related cardiovascular risk, and related comorbidities.
- obesity
- overweight with weight‑related comorbidities
- lipoprotein(a)
- coronary heart disease death
- myocardial infarction and urgent coronary revascularization
Interventions aim to modify body weight and reduce major adverse cardiovascular events.
Gastro‑Esophageal Disease
Targets acid‑related esophageal injury and healing outcomes.
- erosive esophagitis
- gastroesophageal reflux disease
- linaprazan glurate
- lansoprazole comparator
- healing of EE grades C/D
Comparative efficacy studies assess both induction and maintenance phases.
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