Ivan N.
- Country
- Bulgaria
- Department
- Urology department
Research Overview
Data & Insights
Has run more than one trial at 0 of 33 partner sites.
Specializations
Cardiovascular Disease and Heart Failure
The investigator concentrates on conditions such as atherosclerotic cardiovascular disease, myocardial infarction, atrial fibrillation and various forms of heart failure.
- Atherosclerotic cardiovascular disease
- Myocardial infarction (STEMI/NSTEMI)
- Atrial fibrillation
- Heart failure with reduced, mildly reduced or preserved ejection fraction
- Major adverse cardiovascular events
Research aims to lower cardiovascular mortality and hospitalisation rates.
Oncology – Solid Tumors
His work spans multiple malignancies including advanced breast cancer, castration‑resistant prostate cancer, gastric and gastro‑esophageal junction cancer, non‑small cell lung cancer and various lymphomas.
- Advanced breast cancer
- Castration‑resistant prostate cancer
- Gastric and gastro‑esophageal junction cancer
- Non‑small cell lung cancer
- Diffuse large B‑cell lymphoma
Efforts focus on extending progression‑free and overall survival.
Metabolic and Lipid Disorders
He investigates disorders of lipid metabolism such as hypertriglyceridemia, severe hypertriglyceridemia and evaluates novel lipid‑lowering agents.
- Hypertriglyceridemia
- Severe hypertriglyceridemia
- LDL‑C reduction therapies
- Triglyceride lowering agents
- Cardiovascular risk mitigation through lipid control
Goal is to reduce triglyceride levels and associated cardiovascular complications.
Hemostasis and Anticoagulation
His portfolio includes studies on Factor Xa inhibitors, reversal agents, and emerging anticoagulant pathways.
- Factor Xa inhibitor reversal
- Novel oral anticoagulants
- Anticoagulation in atrial fibrillation
- Bleeding risk management during urgent surgery
- FXI inhibition strategies
Research balances thrombotic protection with bleeding safety.
Urologic Oncology
Based in the urology department, he addresses malignancies such as low‑grade upper tract urothelial carcinoma and prostate cancer resistant to hormonal therapy.
- Low‑grade upper tract urothelial carcinoma
- Castration‑resistant prostate cancer
- Urothelial tumor ablation techniques
- Prostate cancer progression management
- Urologic cancer clinical outcomes
Efforts target effective tumor control and quality‑of‑life improvements.
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