Isabelle N. L.
- Country
- France
- Department
- Hépato-Gastro-Entérologie
Research Overview
Data & Insights
Has run more than one trial at 142 of 154 partner sites.
Specializations
Hepatology and Liver Disease
Clinical research activity includes cirrhosis, hepatic encephalopathy, hepatocellular carcinoma, cholangiocarcinoma, and metabolic dysfunction-associated steatotic liver disease, with interest in advanced and decompensated liver conditions.
- Hepatocellular carcinoma
- Primary sclerosing cholangitis
- Non-alcoholic steatohepatitis
- Portal hypertension
Therapeutic involvement also extends to liver complications linked to chronic disease and to interventions supporting disease control in complex digestive and hepatic disorders.
Inflammatory Bowel Disease and Digestive Immunology
The investigator is engaged in trials concerning Crohn’s disease, ulcerative colitis, and broader inflammatory bowel diseases, with additional interest in immune-mediated gastrointestinal inflammation.
- Crohn’s disease
- Ulcerative colitis
- Intestinal failure
- Gastrointestinal motility disorders
Research activity also touches on perianal fistulizing disease and other refractory digestive presentations requiring targeted medical management.
Autoimmune and Systemic Inflammatory Diseases
Clinical interests include systemic lupus erythematosus, Sjögren’s syndrome, systemic sclerosis, vasculitis, sarcoidosis, and related immune-mediated disorders affecting multiple organs.
- Systemic lupus erythematosus
- Sjögren’s syndrome
- Systemic sclerosis
- ANCA-associated vasculitis
The therapeutic landscape also includes inflammatory myopathies, immune thrombocytopenia, and autoinflammatory disease, reflecting work across chronic immune dysregulation.
Respiratory Infection and Mycobacterial Disease
Research involvement covers nontuberculous mycobacterial lung infection, pulmonary infections, and other complex respiratory infectious diseases managed in hospital settings.
- Mycobacterium avium complex
- Bronchiectasis
- Severe influenza
- Hospital-acquired pneumonia
Therapeutic focus includes infection control in chronic lung disease and treatment strategies for persistent or difficult-to-eradicate respiratory pathogens.
Rare Disease and Complex Multisystem Disorders
Additional clinical trial activity includes hereditary transthyretin amyloidosis, kidney disease, myelodysplastic syndromes, and other uncommon conditions requiring specialized medical oversight.
- Hereditary transthyretin amyloidosis
- IgA nephropathy
- Myelodysplastic syndromes
- Systemic mastocytosis
The portfolio also includes neuroimmune and metabolic rare diseases, broadening the therapeutic scope beyond digestive medicine.
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