Irene N.
- Country
- Spain
- Department
- Hematología
Research Overview
- Efficacy and Safety of Oral Decitabine and Ivosidenib in Adults with Newly Diagnosed IDH1-Mutated Acute Myeloid Leukemia Ineligible for Intensive Chemotherapy
- A randomized phase III, global, multicentre, open label clinical trial comparing Venetoclax Azacitidine and Quizartinib vs Venetoclax and Azacitidine in newly diagnosed acute myeloid leukemia patient´s ineligible for standard induction chemotherapy.
Data & Insights
Has run more than one trial at 13 of 42 partner sites.
Specializations
Myeloid Malignancies
Clinical research activity includes acute myeloid leukemia, myelodysplastic syndromes, myeloproliferative neoplasms, and related relapsed or refractory hematologic malignancies. The therapeutic landscape also extends to multiple myeloma, chronic myeloid leukemia, and other blood cancers.
- Acute myeloid leukemia
- Myelodysplastic syndromes
- Multiple myeloma
- Chronic myeloid leukemia
Work in this area is centered on advanced hematology and treatment options for difficult-to-treat malignant disorders.
Thoracic and Solid Tumors
Research involvement spans non-small cell lung cancer, small cell lung cancer, breast cancer, ovarian cancer, renal cell carcinoma, and urothelial carcinoma, with additional interest in head and neck squamous cell carcinoma and colorectal cancer.
- Non-small cell lung cancer
- Small cell lung cancer
- Breast cancer
- Renal cell carcinoma
The therapeutic focus includes advanced and metastatic disease settings, supporting innovation across oncology.
Lymphoid Neoplasms and Cellular Therapy
Clinical interests include diffuse large B-cell lymphoma, mantle cell lymphoma, follicular lymphoma, chronic lymphocytic leukemia, acute lymphoblastic leukemia, and other B-cell and T-cell lymphomas. The portfolio also reflects activity in cellular therapy and transplant-associated complications.
- Diffuse large B-cell lymphoma
- Acute lymphoblastic leukemia
- Chronic lymphocytic leukemia
- Cellular therapy
This area links malignant lymphoid disorders with evolving treatment approaches in refractory disease.
Autoimmune and Inflammatory Disease
Research activity covers rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, systemic lupus erythematosus, Crohn’s disease, ulcerative colitis, myasthenia gravis, and thyroid eye disease.
- Juvenile idiopathic arthritis
- Systemic lupus erythematosus
- Crohn’s disease
- Myasthenia gravis
The therapeutic scope includes immune-mediated disorders affecting the joints, gastrointestinal tract, and endocrine orbit.
Neurology, Transplantation, and Rare Disorders
Additional involvement includes multiple sclerosis, amyotrophic lateral sclerosis, epilepsy, migraine, Parkinson’s disease, Alzheimer’s disease, and muscular dystrophies, together with liver transplantation, lung transplantation, and primary biliary cholangitis.
- Multiple sclerosis
- Amyotrophic lateral sclerosis
- Epilepsy
- Transplantation
This portfolio also reaches into rare neurological diseases, autoimmune liver disease, and post-transplant care.
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