Imke M.
- Country
- Belgium
- Department
- NA
Research Overview
- Efficacy and safety of zenagamtide once-weekly subcutaneous treatment for obesity in adults versus placebo
- Randomized, Placebo‑Controlled Trial of Once‑Daily Oral Semaglutide (1.5, 4, 9 mg) for Weight Loss in Adults with Overweight or Obesity
- Evaluation of Maridebart Cafraglutide Efficacy and Safety in Adults with Obesity or Overweight Without Type 2 Diabetes Mellitus: A Phase 3 Randomized, Double-blind, Placebo-controlled Study
Data & Insights
Has run more than one trial at 11 of 161 partner sites.
Specializations
Endocrine and Metabolic Disorders
Clinical research activity in Endocrinologie includes conditions linked to hormonal regulation, body weight, and metabolic dysfunction, with interest in disorders that affect long-term cardiometabolic health.
- Obesity and overweight
- Weight management
- Diabetes mellitus, type 1
- Severe hypertriglyceridemia
- Metabolic dysfunction-associated steatotic liver disease
Therapeutic interest extends to endocrine complications and metabolic risk reduction, including disorders relevant to lipid metabolism and adrenal function.
Inflammatory Bowel and Hepatobiliary Disease
The investigator is involved in trials addressing chronic gastrointestinal inflammation and cholestatic liver disease, with focus on symptom control and disease modification in immune-mediated digestive disorders.
- Crohn's disease
- Ulcerative colitis
- Primary biliary cholangitis
- Primary sclerosing cholangitis
- Pruritus associated with cholestatic disease
Research activity also covers inflammatory bowel disease complications and liver-related symptoms that require targeted therapeutic management.
Autoimmune and Immune-Mediated Conditions
Work in this area includes systemic and organ-specific immune disorders, with attention to chronic inflammatory conditions affecting the skin, joints, and connective tissue.
- Psoriasis
- Atopic dermatitis
- Hidradenitis suppurativa
- Rheumatoid arthritis
- Systemic sclerosis
Therapeutic involvement also spans juvenile idiopathic arthritis, psoriatic arthritis, and other autoimmune diseases requiring long-term immune modulation.
Respiratory and Infectious Diseases
Clinical trial participation includes respiratory disorders and infection-related conditions, reflecting interest in chronic airway disease, pulmonary inflammation, and prevention of infectious complications.
- Asthma
- Chronic obstructive pulmonary disease
- Bronchiectasis
- Respiratory syncytial virus infection
- Cytomegalovirus infection
Research interest also includes fungal infections, pneumonia, and other respiratory tract diseases where prevention and control of infection are central therapeutic goals.
Cardiometabolic and Renal Comorbidity
The investigator is also engaged in studies of vascular, renal, and blood pressure disorders, particularly where endocrine and metabolic factors intersect with organ protection.
- Hypertension
- Resistant hypertension
- Chronic kidney disease
- Proteinuria
- Atherosclerotic cardiovascular disease
Therapeutic focus includes cardiovascular risk and renal impairment in patients with complex chronic disease.
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