Ignacio D. L. S. G.
- Country
- Spain
- Department
- UCG Enfermedades Infecciosas, Microbiología y Medicina preventiva
Research Overview
- Evaluation of the Antiviral Efficacy and Safety of GSK3739937 in Treatment-Naïve Adults with HIV-1 Infection: A Randomized, Double-Blind, Placebo-Controlled Study
- Evaluation of Preemptive Genotyping Strategy on Statin-Induced Musculoskeletal Adverse Events in Cardiovascular Risk Patients Using Atorvastatin and Drug Combination
- Non-Inferiority Trial Comparing 7-Day Versus 14-Day Linezolid and Drug Combination Regimens for Uncomplicated Enterococcal Bacteremia
Data & Insights
Has run more than one trial at 25 of 143 partner sites.
Specializations
Infectious Diseases and Antimicrobial Therapy
Clinical research activity includes HIV infection, hepatitis B, pulmonary tuberculosis, bacterial pneumonia, sepsis, and invasive candidiasis, with additional interest in gram-negative bacterial infections, bacteremia, and respiratory syncytial virus disease.
- HIV-1 and advanced HIV infection
- Chronic hepatitis B
- Severe bacterial and fungal infections
- Respiratory viral infections
The therapeutic focus also extends to infection prevention and treatment in medically complex patients, including those with late-presenting HIV and serious systemic infection.
Cardiovascular Medicine and Thrombosis Prevention
Research interests include acute myocardial infarction, acute coronary syndrome, atrial fibrillation, stroke prevention, cardiovascular risk reduction, aortic stenosis, and thromboembolic disease, with attention to secondary prevention and antithrombotic strategies.
- Myocardial infarction and ischemic stroke
- Atrial fibrillation and systemic embolism
- Cardiovascular prevention and lipid-related risk
- Valve disease and antiplatelet management
Therapeutic involvement also covers cardiovascular protection in high-risk populations, including patients with cardiorenal disease and those requiring long-term antithrombotic care.
Respiratory and Interstitial Lung Disease
Areas of interest include chronic obstructive pulmonary disease, asthma, idiopathic pulmonary fibrosis, progressive pulmonary fibrosis, interstitial lung diseases, pulmonary sarcoidosis, and respiratory syncytial virus infection in older adults.
- COPD and severe asthma
- Pulmonary fibrosis and fibrotic lung disease
- Pulmonary sarcoidosis
- Respiratory viral disease
Clinical trial involvement reflects a therapeutic emphasis on chronic airway inflammation, fibrosing lung disorders, and symptom control in progressive respiratory disease.
Hematologic Malignancies and Plasma Cell Disorders
Research spans multiple myeloma, chronic lymphocytic leukemia, small lymphocytic lymphoma, follicular lymphoma, marginal zone lymphoma, mantle cell lymphoma, myelodysplastic syndrome, and acute leukemias.
- Multiple myeloma and relapsed disease
- CLL/SLL and lymphoma care
- Myelodysplastic syndromes
- Acute myeloid and acute lymphoblastic leukemia
The therapeutic landscape includes treatment of newly diagnosed, relapsed, and high-risk blood cancers, with interest in immune-based and targeted approaches.
Neurology, Autoimmune Disease, and Metabolic Disorders
Additional activity covers Parkinson’s disease, multiple sclerosis, epilepsy, Alzheimer’s disease, lupus nephritis, rheumatoid arthritis, ulcerative colitis, Crohn’s disease, psoriasis, and type 2 diabetes.
- Parkinsonian disorders and movement symptoms
- Demyelinating disease
- Inflammatory bowel disease and autoimmune inflammation
- Metabolic disease and chronic pain
Therapeutic interests also include pharmacogenetics, pain management, and immune-mediated skin and systemic conditions.
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