Hüsnü B.
- Country
- Germany
- Department
- Augenheilkunde
Research Overview
Data & Insights
Has run more than one trial at 15 of 37 partner sites.
Specializations
Breast Cancer
Clinical research in breast cancer spans HER2-positive, HER2-negative, hormone receptor-positive, triple-negative, and PIK3CA-mutated disease, with interest in both early and advanced settings. The focus includes postoperative residual disease, neoadjuvant treatment, adjuvant escalation, and metastatic disease control.
- HER2-targeted therapy
- Endocrine therapy
- CDK4/6 inhibition
- Antibody-drug conjugates
Work in this area also includes treatment strategies for high-risk disease, ctDNA-positive recurrence, and therapy selection after resistance to prior endocrine or anti-HER2 treatment.
Gynecologic Oncology
Research activity covers epithelial ovarian cancer, fallopian tube cancer, and primary peritoneal cancer, particularly in newly diagnosed advanced-stage disease. The therapeutic emphasis is on systemic disease control in combination with surgery and chemotherapy.
- Platinum-based chemotherapy
- Anti-angiogenic therapy
- PARP inhibition
- Maintenance treatment
Interest extends to advanced-stage disease management, maintenance approaches after initial treatment, and biomarker-informed therapeutic selection in ovarian malignancies.
Colorectal Cancer
Clinical involvement in colon cancer and rectal cancer includes locally advanced and stage II to III disease, with a particular focus on treatment around surgery. The research landscape reflects interest in improving disease control before and after resection.
- Preoperative systemic therapy
- Adjuvant treatment
- ctDNA-guided management
- Recurrence risk reduction
This area includes evaluation of treatment strategies for node-positive and locally advanced disease, with attention to personalized postoperative decision-making.
Retinal Disease
Ophthalmic research includes diabetic macular edema and wet age-related macular degeneration, reflecting a therapeutic interest in retinal vascular disease and vision preservation. The clinical focus is centered on intravitreal treatment approaches for chronic macular pathology.
- Intravitreal therapy
- Visual acuity outcomes
- Anti-VEGF treatment
- Macular edema
These studies address retinal disease burden in conditions associated with diabetes and neovascular degeneration.
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