Hilary O.
- Country
- Ireland
- Department
- Haematology
Research Overview
Data & Insights
Has run more than one trial at 0 of 69 partner sites.
Specializations
Hematologic Malignancies
Hilary O'Leary leads investigations into blood‑borne cancers, emphasizing Acute Myeloid Leukemia and its myelodysplastic precursors.
- Chronic lymphocytic leukemia
- Multiple Myeloma
- Diffuse Large B‑Cell Lymphoma
- Waldenström’s macroglobulinemia
- Myelodysplastic syndromes
Research aims to improve survival and disease‑free intervals for patients across these entities.
Solid Tumor Oncology
The investigator focuses on major solid cancers, including prostate cancer and advanced ovarian epithelial cancer.
- Colorectal cancer
- Stomach cancer
- Esophageal cancer
- Pancreatic cancer
- Fallopian tube cancer
Efforts target novel therapeutic combinations to extend progression‑free survival.
Lung Cancer
Hilary O'Leary contributes to studies of Non‑Small Cell Lung Cancer, with special attention to KRAS‑mutated subtypes.
- Advanced NSCLC
- KRAS‑G12C mutant NSCLC
- Stage IV NSCLC
- Metastatic NSCLC
- Early stage NSCLC
Clinical work seeks to optimize targeted and immunotherapeutic regimens.
Breast Cancer
Her portfolio includes diverse breast‑cancer subtypes, from hormone‑responsive to triple‑negative disease.
- HR‑positive/HER2‑negative early breast cancer
- HER2‑positive breast cancer
- Triple‑negative breast cancer
- High‑risk HER2‑positive breast cancer
- Premenopausal HR‑positive/HER2‑negative breast cancer
The aim is to refine adjuvant strategies and reduce recurrence.
Infectious and Thrombotic Conditions
Beyond oncology, the investigator addresses acute infections and clotting disorders, such as COVID‑19 and venous thromboembolism.
- Cystic Fibrosis
- SARS‑CoV‑2 infection
- Venous thromboembolism
- Stroke
- Surgical site infection
Studies aim to define effective prophylaxis and treatment pathways.
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