Hessam R.
- Country
- France
- Department
- Ophtalmologie
Research Overview
- Dose-ranging study of FWY003 in geographic atrophy secondary to age-related macular degeneration: randomized, double-masked, placebo-controlled trial in adults
- Randomized, Double-Masked, Multicenter Phase 2/3 Trial of Intravitreal MK-8748 Versus Aflibercept in Patients with Neovascular Age‑Related Macular Degeneration
- Phase 2 Randomized Double‑Blind Study of Aganirsen Eye Drops for Extending Intravitreal Aflibercept Injection Intervals in Wet Age‑Related Macular Degeneration
Data & Insights
Has run more than one trial at 76 of 160 partner sites.
Specializations
Neovascular Age-Related Macular Degeneration
Investigation of therapeutic options for Neovascular Age-Related Macular Degeneration emphasizes intravitreal biologics and novel delivery platforms.
- Anti‑VEGF agents
- Bispecific antibodies
- Long‑term visual acuity outcomes
Continued evaluation of efficacy and safety informs clinical practice.
Geographic Atrophy
Research on Geographic Atrophy targets disease‑modifying strategies to slow lesion expansion.
- Complement inhibition
- Oral neuroprotective agents
- Lesion area progression metrics
Focus includes both early‑stage and advanced presentations.
Diabetic Macular Edema
Clinical work addresses Diabetic Macular Edema through optimization of intravitreal therapies and safety profiling.
- Anti‑VEGF comparison studies
- Visual acuity preservation
- Adjunctive treatment assessment
Efforts aim to improve functional outcomes for diabetic patients.
Myopic Choroidal Neovascularization
Exploration of interventions for Myopic Choroidal Neovascularization evaluates efficacy of emerging intravitreal compounds.
- High‑dose anti‑VEGF regimens
- Safety monitoring in high myopia
- Anatomical response imaging
Study designs prioritize visual function preservation.
Retinal Vein Occlusion–related Macular Edema
Focus on treatment pathways for Macular Edema Secondary to Retinal Vein Occlusion includes dosage optimization and long‑term tolerability.
- Extended‑interval dosing
- Comparative efficacy with standard care
- Structural retinal changes
Research supports individualized patient management.
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