Herbert V. W.
- Country
- The Netherlands
- Department
- 031003: Pediatrics
Research Overview
- Pharmacokinetic Evaluation of Infliximab in Pediatric Patients with Crohn's Disease: A Prospective Analysis
- A Phase 3, Multicenter, Randomized, Double-blind, Parallel-group, Safety and Efficacy Study of Linaclotide versus Placebo in Pediatric Subjects, Ages 2 to 5 Years, with Functional Constipation (FC) with a 24-week Open-label Treatment Extension
- A Phase 3, multicentre, randomised (1:1), parallel-group, active-controlled, central reader colonoscopist-blind study to evaluate the bowel cleansing efficacy, safety, tolerability, palatability, and acceptability of PLENVU® as compared to sodium picosulfate in paediatric participants from 1 to < 18 years of age in preparation for colonoscopy (CLARITY)
Data & Insights
Has run more than one trial at 3 of 51 partner sites.
Specializations
Pediatric Gastroenterology
The investigator specializes in treating children with inflammatory bowel disease (IBD), with particular expertise in Crohn's Disease management and therapeutic monitoring.
- Inflammatory Bowel Disease Treatment
- Pediatric Drug Response Monitoring
- Biological Therapy Management
The research focus includes optimization of treatment approaches for pediatric IBD patients using advanced therapeutic monitoring.
Pediatric Functional Disorders
The investigator demonstrates expertise in treating functional gastrointestinal disorders in young children, with specific focus on functional constipation in early childhood.
- Early Childhood Constipation
- Pediatric Functional GI Disorders
- Long-term Treatment Safety
Their work encompasses the evaluation of novel therapeutic approaches for managing functional constipation in children aged 2 to 5 years.
Clinical Therapeutics
The investigator's expertise extends to pharmacological interventions in pediatric gastroenterology, including both biological therapeutics and targeted treatments.
- Therapeutic Drug Monitoring
- Treatment Safety Assessment
- Clinical Efficacy Evaluation
Their research interests include evaluating drug efficacy and safety profiles in pediatric populations with gastrointestinal conditions.
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