H.J. W.
- Country
- The Netherlands
- Department
- Neurology
Research Overview
Data & Insights
Has run more than one trial at 0 of 9 partner sites.
Specializations
Neurodegenerative and Neuromuscular Disorders
Clinical research activity includes amyotrophic lateral sclerosis, spinal muscular atrophy, chronic inflammatory demyelinating polyneuropathy, and other disorders affecting motor and peripheral nerve function.
- Amyotrophic lateral sclerosis
- Spinal muscular atrophy
- Chronic inflammatory demyelinating polyneuropathy
- Refractory epilepsy
- Mild cognitive impairment and dementia
Interest also extends to neuroinflammatory disease, motor neuron disease, and neurological rehabilitation in the setting of progressive disability.
Autoimmune and Immune-Mediated Disease
Research involvement spans systemic sclerosis, systemic lupus erythematosus, rheumatoid arthritis, primary Sjögren's syndrome, and related immune-mediated conditions.
- Systemic sclerosis
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Primary Sjögren's syndrome
- Idiopathic inflammatory myopathies
Additional activity includes inflammatory bowel disease, juvenile idiopathic arthritis, and immune thrombocytopenia, reflecting a broad focus on immune dysregulation.
Cardiovascular and Vascular Medicine
The investigator is engaged in studies of atherosclerotic cardiovascular disease, heart failure, atrial fibrillation, and hypertension, with attention to vascular risk and thrombotic complications.
- Atherosclerotic cardiovascular disease
- Heart failure
- Atrial fibrillation
- Hypertension
- Peripheral arterial disease
Research also covers stroke, coronary artery disease, and lipid disorders, including conditions linked to elevated cardiovascular risk.
Hematologic Malignancies and Cellular Therapy
Clinical interests include non-Hodgkin lymphoma, multiple myeloma, acute leukemia, and other blood cancers, alongside advanced treatment platforms.
- Non-Hodgkin lymphoma
- Multiple myeloma
- Acute myeloid leukemia
- Chronic lymphocytic leukemia
- CAR T-cell therapy
Work in this area also involves relapsed or refractory hematologic malignancies and gene-modified T-cell therapies.
Oncology, Gastroenterology, and Rare Disease
Research activity extends across solid tumors, including lung cancer, colorectal cancer, breast cancer, ovarian cancer, and urothelial carcinoma, as well as digestive and hepatobiliary malignancies.
- Non-small cell lung cancer
- Colorectal cancer
- Ovarian cancer
- Crohn's disease
- Cystic fibrosis
Additional interests include gastrointestinal inflammation, rare metabolic disease, and amyloidosis, reflecting involvement in both common and uncommon therapeutic areas.
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