Heloise I.
- Country
- France
- Department
- neurologie
Research Overview
Data & Insights
Has run more than one trial at 0 of 7 partner sites.
Specializations
Neurodegenerative & Neuromuscular Disorders
Focused on diseases of the central and peripheral nervous system that affect cognition, motor function and survival.
- Alzheimer’s disease psychosis
- Amyotrophic lateral sclerosis
- Diffuse intrinsic pontine glioma
- Multiple sclerosis (including secondary progressive)
- Peripheral neuropathies such as chronic inflammatory demyelinating polyneuropathy
Research is conducted at the Centre Hospitalier Regional Universitaire De Tours within the neurology department.
Oncology & Hematology
Investigation of solid tumors and hematologic malignancies across all disease stages.
- Non‑small cell lung cancer
- Metastatic colorectal cancer with KRAS G12C mutation
- Acute myeloid leukemia (including IDH1‑mutated)
- Multiple myeloma (including relapsed/refractory)
- High‑grade B‑cell lymphoma
The investigator contributes to therapeutic advances in cancer and blood‑cell disorders.
Cardiovascular & Metabolic Diseases
Emphasis on acute coronary events, heart failure phenotypes and metabolic risk factors.
- Acute myocardial infarction (STEMI/NSTEMI)
- Heart failure with preserved ejection fraction
- Atherosclerotic cardiovascular disease
- Type 2 diabetes with obesity
- Hypertension (including resistant forms)
Clinical work integrates cardiology and metabolic care pathways.
Autoimmune & Inflammatory Conditions
Targeted studies on systemic and organ‑specific autoimmune diseases.
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Psoriatic arthritis
- ANCA‑associated vasculitis
- Inflammatory bowel disease (ulcerative colitis and Crohn’s disease)
Research aims to improve disease‑modifying strategies for immune‑mediated disorders.
Renal, Hepatic & Transplant Medicine
Studies addressing organ failure, transplant complications and metabolic liver disease.
- Acute kidney injury (including sepsis‑associated)
- Chronic kidney disease with proteinuria
- Hepatic encephalopathy in acute‑on‑chronic liver failure
- Kidney transplantation rejection and BKV infection
- Transthyretin amyloid cardiomyopathy
The work supports multidisciplinary management of organ dysfunction and transplant outcomes.
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