Helle P.
- Country
- Denmark
- Department
- Urooncology
Research Overview
- Phase 3 Study of Vepugratinib and Combination Therapy in Adults with Untreated FGFR3-Altered Locally Advanced or Metastatic Urothelial Carcinoma
- A Phase 3 Randomized, Double-blind, Multi-center Study of Adjuvant Nivolumab versus Placebo in Subjects with High Risk Invasive Urothelial Carcinoma
- Evaluation of Perioperative Pembrolizumab and Enfortumab Vedotin with Cystectomy Versus Cystectomy Alone in Cisplatin-Ineligible Muscle-Invasive Bladder Cancer
Data & Insights
Has run more than one trial at 64 of 226 partner sites.
Specializations
Urothelial Cancer Management
The investigator specializes in treating various stages of urothelial carcinoma, with particular expertise in both localized and metastatic disease states. Their research encompasses novel approaches for bladder cancer treatment, including post-surgical monitoring and therapeutic interventions.
- Metastatic Disease Management
- Post-Radical Cystectomy Care
- Advanced Urothelial Carcinoma
Their work includes innovative monitoring techniques using circulating tumor DNA for early detection of disease recurrence.
Immunotherapy Applications
The investigator focuses on advancing immunotherapeutic approaches in urological cancers, particularly exploring the role of PD-1/PD-L1 targeted agents. Their research includes both single-agent and combination therapy strategies.
- Novel Immunotherapy Combinations
- Treatment-Resistant Disease
- Biomarker-Driven Therapies
A key area of focus is developing treatments for patients with PD-1/L1 refractory disease.
Prostate Cancer Research
The investigator conducts research in metastatic castration-resistant prostate cancer, exploring innovative combination therapies. Their work includes investigation of novel drug combinations with established treatments.
- Treatment-Resistant Disease
- Biomarker Studies
- Combination Therapy Approaches
Their research includes evaluation of biochemical response markers in prostate cancer treatment.
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