Helle H.
- Country
- Denmark
- Department
- Department of Nephrology
Research Overview
Data & Insights
Has run more than one trial at 0 of 2 partner sites.
Specializations
Kidney Disease
The investigator concentrates on disorders affecting renal function and progression to end‑stage renal disease.
- Chronic kidney disease
- End‑stage renal disease
- Diabetic nephropathy
- Hypertension‑related kidney injury
- Complement‑mediated kidney injury
Research is conducted at Sydvestjysk Sygehus.
Cardiovascular Disease
Focus includes atherosclerotic disease, heart failure, and thrombo‑embolic disorders.
- Atherosclerotic cardiovascular disease
- Heart failure with reduced ejection fraction
- Atrial fibrillation
- Major adverse cardiovascular events
- Lipoprotein(a) lowering
Studies address both primary and secondary prevention.
Metabolic and Liver Disorders
Research targets metabolic syndrome components and progressive liver injury.
- Non‑alcoholic steatohepatitis
- Type 2 diabetes
- Obesity
- Dyslipidemia
- Hypertriglyceridemia
Investigations explore insulin resistance and hepatic lipogenesis.
Respiratory Disorders
The investigator evaluates chronic obstructive pulmonary disease and related exacerbation management.
- COPD
- Eosinophil‑guided inhaled corticosteroid reduction
- Azithromycin prophylaxis
- Severe COPD
- Acute exacerbations
Trials assess outcomes in advanced GOLD classes.
Autoimmune and Inflammatory Conditions
Work includes immune‑mediated arthritis, inflammatory bowel disease, and demyelinating disorders.
- Psoriatic arthritis
- Ulcerative colitis
- Crohn’s disease
- Multiple sclerosis
- Polymyalgia rheumatica
Therapeutic strategies involve biologics and targeted small molecules.
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