Helene B.
- Country
- France
- Department
- 250004:Cardiologie
Research Overview
- Phase 2 Study of REGN13335 Efficacy and Safety in Adults with Pulmonary Arterial Hypertension
- Evaluation of Reduced-Dose Alteplase in Intermediate-High-Risk Acute Pulmonary Embolism: A Randomized Controlled Trial
- Comparison of Initial Dual Oral Therapy with Riociguat and Macitentan Versus Standard Monotherapy in Inoperable Chronic Thromboembolic Pulmonary Hypertension
Data & Insights
Has run more than one trial at 13 of 79 partner sites.
Specializations
Cardiovascular Medicine
Helene Bouvaist is involved in clinical research on acute myocardial infarction, acute coronary syndrome, atherosclerotic cardiovascular disease, heart failure, and arrhythmia-related conditions, with additional interest in atrial fibrillation, pulmonary hypertension, and hypertrophic cardiomyopathy.
- Myocardial infarction
- Heart failure
- Atrial fibrillation
- Pulmonary arterial hypertension
Her cardiology activity at CHU Grenoble Alpes also extends to vascular disease, stroke prevention, and structural heart disease.
Respiratory Disease
Her research landscape includes obstructive sleep apnea, asthma, chronic obstructive pulmonary disease, interstitial lung disease, and idiopathic pulmonary fibrosis, reflecting sustained involvement in chronic and progressive respiratory disorders.
- Obstructive sleep apnea
- Severe asthma
- COPD
- Interstitial lung disease
She is also linked to research on pulmonary arterial hypertension, severe pneumonia, and other complex respiratory conditions requiring specialist care.
Renal and Transplant Medicine
Helene Bouvaist is active in studies of chronic kidney disease, IgA nephropathy, focal segmental glomerulosclerosis, and kidney transplantation, including antibody-mediated rejection and renal allograft rejection.
- Chronic kidney disease
- IgA nephropathy
- Kidney transplantation
- Antibody-mediated rejection
Her therapeutic focus also covers proteinuric kidney disease, delayed graft function, and transplant-related immune complications.
Oncology and Hematology
Her trial portfolio spans lung cancer, breast cancer, hepatocellular carcinoma, colorectal cancer, and urothelial carcinoma, alongside hematologic malignancies such as acute myeloid leukemia, acute lymphoblastic leukemia, lymphoma, multiple myeloma, and myelodysplastic syndrome.
- Non-small cell lung cancer
- Acute myeloid leukemia
- Diffuse large B-cell lymphoma
- Hepatocellular carcinoma
She is also involved in research on solid tumors, melanoma, and gastrointestinal cancers, with emphasis on advanced and refractory disease settings.
Autoimmune and Inflammatory Disorders
Her clinical research also includes rheumatoid arthritis, systemic sclerosis, systemic lupus erythematosus, vasculitis, ulcerative colitis, and Crohn’s disease, as well as Sjögren’s syndrome and giant cell arteritis.
- Rheumatoid arthritis
- Systemic sclerosis
- Inflammatory bowel disease
- Vasculitis
She is additionally connected to research on urticaria, psoriatic arthritis, and other immune-mediated disorders.
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