Heino-Enn A.
- Country
- Estonia
- Department
- Department of Urology
Research Overview
- Phase 3 Randomized Study of Tebipenem Pivoxil Hydrobromide vs. Imipenem-Cilastatin in Complicated Urinary Tract Infection and Acute Pyelonephritis
- Evaluation of UGN-103 (Mitomycin) Efficacy and Safety in Intermediate-Risk Low-Grade Nonmuscle Invasive Bladder Cancer: A Phase 3 Single-Arm Study
- Phase 3 Multicenter Evaluation of UGN-102 (Mitomycin) Efficacy and Safety in Low Grade Non-Muscle-Invasive Bladder Cancer at Intermediate Recurrence Risk
Data & Insights
Has run more than one trial at 23 of 80 partner sites.
Specializations
Atherosclerotic and Cardioembolic Stroke Prevention
Clinical research activity includes prevention of acute ischemic stroke and high-risk transient ischemic attack, with a strong focus on thromboembolic risk reduction in atrial fibrillation and related systemic embolism prevention.
- Acute ischemic stroke and high-risk transient ischemic attack
- Atrial fibrillation
- Stroke or systemic embolism prevention
The therapeutic landscape also includes cardiovascular risk management in patients with end-stage kidney disease and atherosclerotic cardiovascular disease.
Inflammatory Bowel Disease
The investigator is involved in treatment studies for ulcerative colitis and Crohn's disease, covering both active disease control and longer-term maintenance care in moderately to severely active disease.
- Ulcerative colitis
- Crohn's disease
- Maintenance therapy
Research interest extends to biologic and targeted approaches for inflammatory bowel disease, including strategies aimed at sustained remission and disease control.
Neuroimmunology and Multiple Sclerosis
Clinical trial involvement includes multiple sclerosis, with attention to relapsing multiple sclerosis and long-term management of immune-mediated neurological disease.
- Multiple sclerosis
- Relapsing multiple sclerosis
- Long-term safety
This area reflects ongoing work in neuroimmunology and durable disease-modifying treatment options.
Renal Disease and Proteinuric Kidney Disorders
The investigator participates in studies addressing focal segmental glomerulosclerosis and immunoglobulin A nephropathy, with emphasis on preservation of renal function and reduction of proteinuria.
- Focal segmental glomerulosclerosis
- Immunoglobulin A nephropathy
- Proteinuria and renal function preservation
Additional interest includes inflammatory kidney disease in patients with end-stage kidney disease undergoing dialysis.
Infectious Disease and Urologic Oncology
Research activity also covers treatment of complicated urinary tract infection and acute pyelonephritis, alongside studies in non-muscle invasive bladder cancer.
- Complicated urinary tract infection and acute pyelonephritis
- Non-muscle invasive bladder cancer
- Hospitalized adult patients
The clinical portfolio combines antimicrobial therapy with urologic cancer management in adult care settings.
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