Guzman A.
- Country
- Spain
- Department
- Next Oncology Barcelona IOB
Research Overview
- Phase 1 Study of SHP2 Inhibitor BBP-398 and KRAS-G12C Inhibitor Sotorasib in Advanced Solid Tumors with KRAS-G12C Mutation
- Phase I Clinical Trial of TOS-358 in Adult Patients with Advanced Solid Tumors: Colorectal, Cervical, Endometrial, Gastric, Urothelial, Breast, Head and Neck, Ovarian, and NSCLC.
- Phase I Evaluation of FS222 for Safety and Efficacy in Patients with Advanced Malignancies
Data & Insights
Has run more than one trial at 52 of 136 partner sites.
Specializations
Advanced Cancer Research
This investigator specializes in treating advanced solid tumors with a particular focus on genetic mutations and targeted therapies. Their expertise extends to studying novel therapeutic combinations for patients with KRASG12C mutations and HER2 genetic alterations.
- Mutation-Specific Treatments
- Combined Therapeutic Approaches
- Advanced Stage Cancers
Their work encompasses innovative treatment strategies for various types of solid tumors, including targeted molecular therapies.
Specialized Cancer Types
The investigator focuses on multiple specific cancer types, including non-small cell lung cancer, colorectal cancer, and breast cancer. They have particular expertise in treating HER2-positive tumors and cancers with specific genetic markers.
- Esophageal Cancer
- Metastatic Breast Cancer
- Colorectal Cancer
Their research includes both monotherapy and combination treatment approaches for these specific cancer types.
Novel Therapeutic Applications
The investigator studies innovative treatment combinations including immunotherapy approaches and targeted molecular therapies. Their work involves evaluating new drug combinations and their safety profiles in treating advanced cancers.
- Combination Therapies
- Immunotherapy Integration
- Targeted Treatment Protocols
Their research includes investigating novel drug combinations with established cancer treatments to enhance therapeutic outcomes.
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