Gurvan D.
- Country
- France
- Department
- radiothérapie
Research Overview
- Phase III Multicenter Randomized Controlled Double-Blind Study of Bevacizumab Versus Placebo in Corticodependent or Corticoresistant Brain Radionecrosis Post-Radiotherapy for Brain Metastases
- Phase I/II Evaluation of Gadolinium-Chelated Polysiloxane Nanoparticles with Radiotherapy and Temozolomide in Newly Diagnosed Glioblastoma
Data & Insights
Has run more than one trial at 3 of 25 partner sites.
Specializations
Radiation Oncology and Local Cancer Control
Clinical research activity in radiotherapy at the Centre Hospitalier Regional Et Universitaire De Brest includes cancer-focused studies centered on thoracic malignancies, gastrointestinal cancers, urothelial carcinoma, and other solid tumors requiring local treatment strategies.
- Non-Small Cell Lung Cancer
- Gastric and Gastroesophageal Junction Cancer
- Urothelial Cancer
- Head and Neck Squamous Cell Carcinoma
- Metastatic Solid Tumors
The therapeutic focus extends to stereotactic radiotherapy, adjuvant treatment, and metastatic disease control across multiple tumor types.
Hematology and Stem Cell Transplantation
The investigator is involved in hematologic malignancies and transplant-related care, with interest in acute lymphoblastic leukemia, acute myeloid leukemia, myelodysplastic syndromes, and lymphoma, as well as allogeneic hematopoietic stem cell transplantation.
- Acute Lymphoblastic Leukemia
- Acute Myeloid Leukemia
- Myelodysplastic Syndrome
- Myelofibrosis
- B-cell Lymphoma
Research activity also covers relapsed disease, high-risk hematologic profiles, and post-transplant therapeutic optimization.
Autoimmune, Inflammatory, and Neurological Disorders
Clinical interests include autoimmune disease and immune-mediated inflammation, especially rheumatoid arthritis, systemic lupus erythematosus, Sjögren's syndrome, vasculitis, and myelin-associated demyelinating disease.
- Rheumatoid Arthritis
- Systemic Lupus Erythematosus
- Sjögren's Syndrome
- ANCA-Associated Vasculitis
- Multiple Sclerosis
Additional work includes neuropathic disorders, demyelinating syndromes, and immune neuropathy.
Respiratory, Cardiovascular, and Critical Care Medicine
Research activity spans pulmonary hypertension, severe asthma, interstitial lung disease, sepsis, septic shock, and cardiac rhythm disorders, with attention to acute and chronic organ dysfunction.
- Pulmonary Arterial Hypertension
- Septic Shock
- Atrial Fibrillation
- Heart Failure
- Ischemic Stroke
Therapeutic interests also include thromboembolic disease, cardiovascular prevention, and respiratory failure.
Kidney Disease, Transplantation, and Rare Immune-Mediated Conditions
The clinical portfolio includes chronic kidney disease, autosomal dominant polycystic kidney disease, kidney transplantation, and glomerular disease, alongside selected rare inflammatory and dermatologic disorders.
- Chronic Kidney Disease
- Autosomal Dominant Polycystic Kidney Disease
- Kidney Transplantation
- Atopic Dermatitis
- Hidradenitis Suppurativa
Research interests also extend to renal vasculitis, immune thrombocytopenia, and rare antibody-mediated disease.
Related Investigators
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