Guillaume F.
- Country
- France
- Department
- Service de Néphrologie (CHU Pasteur)
Research Overview
- Effect of Empagliflozin on Proteinuria in Patients with Type 2 Diabetes and Renal Impairment (eGFR 10-20 ml/min/1.73m2)
- Evaluation of Zibotentan and Dapagliflozin Combination Versus Dapagliflozin Monotherapy in Chronic Kidney Disease with High Proteinuria: A Phase III Randomized Study
- Efficacy and Safety of Baxdrostat and Dapagliflozin on Renal and Cardiovascular Outcomes in Chronic Kidney Disease with Hypertension
Data & Insights
Has run more than one trial at 64 of 384 partner sites.
Specializations
Kidney disease and nephrology
Guillaume Favre’s clinical research profile is anchored in nephrology, with activity spanning chronic kidney disease, end-stage renal disease, glomerular diseases, and kidney transplantation. His interests also extend to renal complications linked to diabetes, hypertension, and proteinuria.
- Immunoglobulin A nephropathy
- Focal segmental glomerulosclerosis
- Membranous nephropathy
- Renal transplant
His trial landscape includes renal immune-mediated disorders and transplant-related conditions, reflecting involvement in therapeutic innovation for progressive kidney injury and immune-driven renal disease.
Autoimmune and inflammatory diseases
He is involved in studies of systemic and organ-specific inflammatory disorders, including rheumatoid arthritis, systemic lupus erythematosus, vasculitis, and systemic sclerosis. Additional interests include myositis, myasthenia gravis, and psoriatic disease.
- Rheumatoid arthritis
- Systemic lupus erythematosus
- ANCA-associated vasculitis
- Myasthenia gravis
His research also covers inflammatory bowel disease and dermatologic autoimmunity, including ulcerative colitis, Crohn’s disease, vitiligo, and atopic dermatitis.
Hematologic malignancies and blood disorders
Another major area of interest is hematology, with trials involving acute myeloid leukemia, myelodysplastic syndromes, acute lymphoblastic leukemia, and multiple myeloma. His portfolio also includes myelofibrosis and other myeloid neoplasms.
- Acute myeloid leukemia
- Myelodysplastic syndromes
- Acute lymphoblastic leukemia
- Multiple myeloma
He is also engaged in research on relapsed or refractory blood cancers and transplant-associated complications, supporting the development of new treatment options in difficult-to-treat hematologic disease.
Cardiovascular and thrombotic disease
His clinical trial activity includes atherosclerotic cardiovascular disease, myocardial infarction, stroke prevention, atrial fibrillation, and heart failure. He also has interest in pulmonary hypertension and vascular inflammation.
- Atherosclerotic cardiovascular disease
- Acute myocardial infarction
- Ischemic stroke
- Pulmonary arterial hypertension
These studies place emphasis on prevention of major vascular events and treatment of cardiopulmonary vascular syndromes.
Pulmonary, neurologic, and dermatologic conditions
He is also involved in trials across interstitial lung disease, idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease, and bronchiectasis, alongside neurologic disorders such as multiple sclerosis, Parkinson’s disease, and amyotrophic lateral sclerosis.
- Idiopathic pulmonary fibrosis
- Multiple sclerosis
- Parkinson’s disease
- Hidradenitis suppurativa
His dermatology-related research further includes psoriasis, bullous pemphigoid, and vitiligo, broadening his therapeutic scope across immune-mediated skin and systemic diseases.
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