Guillaume E.
- Country
- France
- Department
- hematology
Research Overview
- TRANSCRIPT: An open label, controlled, randomized multicentric international study evaluating the benefit of autologous stem cell transplantation after complete response in frontline setting patients with T cell-lymphoma
- Phase 2 Randomized Study of Elranatamab and Lenalidomide Versus Daratumumab and Lenalidomide for Post-Transplant Maintenance in Newly Diagnosed Multiple Myeloma
Data & Insights
Has run more than one trial at 22 of 72 partner sites.
Specializations
Hematologic Malignancies and Stem Cell Transplantation
Clinical activity in acute myeloid leukemia, acute lymphoblastic leukemia, myelodysplastic syndromes, myeloproliferative neoplasms, multiple myeloma, lymphoma, Waldenström macroglobulinemia, and plasma cell disorders, with strong involvement in allogeneic hematopoietic stem cell transplantation and post-transplant maintenance.
- Acute leukemia
- Myelodysplastic syndromes and myelofibrosis
- Multiple myeloma and relapsed/refractory lymphoma
- Hematopoietic stem cell transplantation
The research profile also includes graft-versus-host disease, immune thrombocytopenia, and other blood cancers requiring specialized hematology care.
Cardiovascular and Thrombotic Disease
Active interest in atherosclerotic cardiovascular disease, lipoprotein(a)-related risk, heart failure, atrial fibrillation, cardiac arrest, stroke, peripheral arterial disease, and venous thromboembolism.
- Cardiovascular prevention
- Arrhythmia management
- Post-resuscitation care
- Thrombosis and vascular disease
Therapeutic focus extends to myocardial infarction, coronary syndrome, cardiomyopathy, and post-cardiac surgery outcomes.
Gastroenterology, Hepatology, and Inflammatory Bowel Disease
Research involvement spans Crohn’s disease, ulcerative colitis, primary sclerosing cholangitis, metabolic dysfunction-associated steatotic liver disease, metabolic dysfunction-associated steatohepatitis, and hepatocellular carcinoma.
- Crohn’s disease and ulcerative colitis
- Cholestatic and fatty liver disease
- Gastrointestinal cancer
- Pancreatic and colorectal surgery
Additional activity includes colorectal cancer, gastric cancer, pancreatic adenocarcinoma, and postoperative digestive complications.
Respiratory, Infectious, and Critical Care Medicine
Therapeutic interests cover chronic pulmonary aspergillosis, Mycobacterium avium complex lung infection, bronchiectasis, idiopathic pulmonary fibrosis, severe asthma, pneumonia, and ventilator-associated pneumonia.
- Pulmonary infections
- Interstitial lung disease
- Intensive care
- Sepsis and shock
Research also includes cardiorespiratory arrest, hemoptysis, invasive fungal disease, and septic shock in critically ill patients.
Autoimmune, Neurological, and Dermatologic Disorders
Clinical work extends to multiple sclerosis, migraine, Alzheimer’s disease, Parkinson’s disease, autoimmune vasculitis, systemic sclerosis, rheumatoid arthritis, and atopic dermatitis.
- Neuroinflammatory disease
- Autoimmune vasculitis
- Skin and mucosal inflammatory disease
- Neuropathic pain
The portfolio also includes hidradenitis suppurativa, pemphigus, psoriasis, prurigo nodularis, and chronic pain syndromes.
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