Guilherme M.
- Country
- Portugal
- Department
- Gastroenterology department
Research Overview
Data & Insights
Has run more than one trial at 2 of 107 partner sites.
Specializations
Inflammatory Bowel Disease and Digestive Inflammation
Clinical research activity is centred on gastroenterology, with a strong focus on Crohn’s disease, ulcerative colitis, and broader inflammatory bowel disease. The portfolio also includes studies in eosinophilic esophagitis and erosive esophagitis, reflecting interest in inflammatory and immune-mediated disorders of the digestive tract.
- Crohn’s Disease
- Ulcerative Colitis
- Inflammatory Bowel Diseases
- Eosinophilic Esophagitis
- Erosive Esophagitis
Work in this area aligns with advanced therapeutic development for chronic intestinal inflammation and treatment-resistant disease.
Immune-Mediated Skin Disease
The investigator is involved in clinical research on atopic dermatitis and hidradenitis suppurativa, with additional interest in psoriatic arthritis and other inflammatory skin conditions. These studies place emphasis on immune-driven dermatologic disease requiring systemic therapy.
- Atopic Dermatitis
- Moderate to Severe Atopic Dermatitis
- Hidradenitis Suppurativa
- Psoriatic Arthritis
The therapeutic scope includes targeted immunomodulatory approaches for chronic relapsing skin disease.
Renal and Metabolic Disorders
Research interests extend to IgA nephropathy, focal segmental glomerulosclerosis, chronic kidney disease, and Wilson disease. The investigator also participates in studies related to obesity, type 2 diabetes, and non-alcoholic steatohepatitis, indicating engagement with metabolic disease and organ-specific complications.
- IgA Nephropathy
- Focal Segmental Glomerulosclerosis
- Chronic Kidney Disease
- Wilson Disease
- Type 2 Diabetes
This area reflects therapeutic interest in renal preservation, metabolic control, and disease modification in chronic systemic conditions.
Cardiovascular and Cerebrovascular Disease
Clinical trial involvement includes heart failure, atrial fibrillation, arterial hypertension, atherosclerotic cardiovascular disease, and ischemic stroke. The portfolio also covers severe aortic stenosis and transthyretin-mediated amyloid cardiomyopathy, showing a broad cardiovascular therapeutic interest.
- Heart Failure
- Atrial Fibrillation
- Ischemic Stroke
- Atherosclerotic Cardiovascular Disease
- Transthyretin-Mediated Amyloid Cardiomyopathy
These studies are oriented toward improving outcomes in high-risk cardiovascular and vascular disease.
Neurology, Oncology, and Other Systemic Conditions
Additional clinical research activity spans epilepsy, migraine, Parkinson’s disease, multiple sclerosis, and selected oncology settings such as breast cancer and non-small cell lung cancer. The investigator is also involved in trials for cystic fibrosis, pulmonary arterial hypertension, and haemophilia, indicating a wide therapeutic reach beyond digestive medicine.
- Epilepsy
- Migraine
- Parkinson’s Disease
- Breast Cancer
- Non-Small Cell Lung Cancer
The research landscape includes innovative therapies across neurological, oncologic, respiratory, and hematologic disease areas.
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