Guido Alessandro P.
- Country
- Italy
- Department
- Neuroscienze
Research Overview
Data & Insights
Has run more than one trial at 5 of 5 partner sites.
Specializations
Neurodegenerative and movement disorders
Clinical research interest includes Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, progressive supranuclear palsy, and multiple system atrophy, with attention to cognitive decline, psychosis, and autonomic symptoms.
- Alzheimer’s disease
- Parkinson’s disease
- Multiple sclerosis
- Progressive supranuclear palsy
- Multiple system atrophy
Also involved in studies of cognitive impairment, neuropsychiatric symptoms, and neurogenic orthostatic hypotension.
Autoimmune and inflammatory diseases
Research activity spans systemic lupus erythematosus, lupus nephritis, systemic sclerosis, rheumatoid arthritis, and Sjögren’s syndrome, alongside other immune-mediated conditions.
- Systemic lupus erythematosus
- Lupus nephritis
- Systemic sclerosis
- Rheumatoid arthritis
- Sjögren’s syndrome
Additional involvement includes myasthenia gravis, idiopathic inflammatory myopathy, psoriatic arthritis, atopic dermatitis, and vitiligo.
Gastroenterology and hepatology
Therapeutic focus includes Crohn’s disease, ulcerative colitis, non-alcoholic steatohepatitis, primary biliary cholangitis, and alcohol-related liver disease.
- Crohn’s disease
- Ulcerative colitis
- Non-alcoholic steatohepatitis
- Primary biliary cholangitis
- Alcohol-related liver disease
Further interests extend to fibrosis, cholestatic pruritus, intestinal malabsorption, and short bowel syndrome.
Oncology and hematologic malignancies
Clinical trial involvement covers breast cancer, ovarian cancer, non-small cell lung cancer, colorectal cancer, and endometrial cancer, with parallel activity in blood cancers.
- Breast cancer
- Ovarian cancer
- Non-small cell lung cancer
- Colorectal cancer
- Endometrial cancer
Additional areas include acute myeloid leukemia, chronic lymphocytic leukemia, diffuse large B-cell lymphoma, multiple myeloma, and myelodysplastic syndrome.
Cardiometabolic, respiratory, and rare disease therapeutics
Research interests also include atherosclerotic cardiovascular disease, myocardial infarction, heart failure, type 2 diabetes, obesity, asthma, and chronic obstructive pulmonary disease.
- Atherosclerotic cardiovascular disease
- Myocardial infarction
- Type 2 diabetes
- Asthma
- Chronic obstructive pulmonary disease
Rare disease activity includes myotonic dystrophy, spinal muscular atrophy, duchenne muscular dystrophy, Fabry disease, and hereditary transthyretin amyloidosis.
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