Griet V. L.
- Country
- Belgium
- Department
- DRUG
Research Overview
- Evaluation of MK-4082 for Weight Management in Healthy Individuals: A Phase I Clinical Trial
- A Phase I Study to Evaluate the Effect of Different Liquid Vehicles on the Pharmacokinetics of MK-3214 in Healthy Volunteers with Hypercholesterolaemia
- A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of MK-4605 in Healthy Participants
Data & Insights
Has run more than one trial at 1 of 2 partner sites.
Specializations
Gastroenterology and Hepatology
Clinical activity includes Crohn’s disease, ulcerative colitis, primary biliary cholangitis, primary sclerosing cholangitis, and related cholestatic pruritus, with additional interest in metabolic dysfunction-associated steatotic liver disease and non-alcoholic steatohepatitis.
- Inflammatory bowel disease
- Autoimmune liver disease
- Pruritus management
Research involvement also extends to hepatocellular carcinoma and other digestive system diseases, reflecting a strong therapeutic focus on chronic immune-mediated and hepatobiliary disorders.
Hematologic Malignancies
The investigator is active in acute lymphoblastic leukemia, acute myeloid leukemia, lymphoma, multiple myeloma, and myelodysplastic syndrome, including settings of relapse, refractoriness, and high-risk disease.
- B-cell and T-cell neoplasms
- Myeloid malignancies
- Cell therapy
Additional interest is seen in hematopoietic stem cell transplantation, graft-versus-host disease, and antibody-mediated rejection in transplant-related care.
Solid Tumors and Oncology
Clinical research spans breast cancer, lung cancer, ovarian cancer, endometrial cancer, prostate cancer, colorectal cancer, and head and neck squamous cell carcinoma, across locally advanced, metastatic, and recurrent disease.
- Genitourinary cancers
- Thoracic oncology
- Gynecologic malignancies
Work also includes gastroesophageal cancer, renal cell carcinoma, bladder cancer, and broader solid tumor treatment strategies.
Autoimmune and Inflammatory Diseases
The investigator is involved in studies of psoriasis, atopic dermatitis, hidradenitis suppurativa, rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis, and systemic lupus erythematosus.
- Rheumatologic disease
- Dermatologic inflammation
- Systemic autoimmune conditions
Further activity includes systemic sclerosis, Sjögren’s syndrome, and myositis, highlighting a therapeutic interest in immune-mediated multisystem disorders.
Respiratory, Neurologic, and Metabolic Disorders
Research extends to asthma, chronic obstructive pulmonary disease, bronchiectasis, interstitial lung disease, and idiopathic pulmonary fibrosis, alongside neurologic and metabolic conditions.
- Multiple sclerosis
- Stroke
- Obesity and weight management
Additional clinical interests include migraine, epilepsy, Alzheimer’s disease, chronic kidney disease, and cardiovascular disease, showing engagement with complex chronic disease areas.
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