Grégoire L. G.
- Country
- France
- Department
- Réanimation CTCV
Research Overview
Data & Insights
Has run more than one trial at 3 of 11 partner sites.
Specializations
Hematologic Malignancies
The investigator focuses on malignant disorders of the blood and bone marrow, addressing both acute and chronic disease entities.
- Acute Myeloid Leukemia
- Acute Lymphoblastic Leukemia
- Chronic Lymphocytic Leukemia
- Diffuse Large B‑Cell Lymphoma
- Follicular Lymphoma
- Richter Syndrome
- Myelodysplastic Syndrome
- Large Granular Lymphocytic Leukemia
- Blastic Plasmacytoid Dendritic Cell Neoplasm
Therapeutic efforts span targeted agents, immunotherapies, and conditioning regimens for allogeneic transplantation.
Solid Tumor Oncology
Research addresses a broad spectrum of epithelial cancers, with emphasis on molecularly defined subgroups.
- Non‑Small Cell Lung Cancer
- Small Cell Lung Cancer
- Pancreatic Neuroendocrine Carcinoma
- Colorectal Cancer
- Prostate Cancer
- Breast Cancer
- Biliary Tract Carcinoma
- Gastro‑Entero‑Pancreatic Neuroendocrine Tumors
- High‑Risk Large B‑Cell Lymphoma
Key interests include KRAS‑G12C mutations, HER2 alterations, and strategies for neoadjuvant and metastatic disease.
Cardiovascular & Metabolic Medicine
Investigations target atherothrombotic disease and related vascular conditions.
- Atherosclerotic Cardiovascular Disease
- Peripheral Arterial Disease
- Hypertension in Chronic Kidney Disease
- Pre‑eclampsia Prevention
- Stroke Prevention in Atrial Fibrillation
- Symptomatic Obstructive Hypertrophic Cardiomyopathy
Therapeutic focus includes antiplatelet strategies, lipid‑lowering agents, and blood‑pressure modulation.
Neurological & Neurodegenerative Disorders
Clinical work encompasses both degenerative and developmental neurologic conditions.
- Parkinson’s Disease
- Alzheimer’s Disease
- Multiple Sclerosis
- Tuberous Sclerosis Complex–related Epilepsy
- Brain Stem Gliomas
- Epilepsy
- Transthyretin Amyloidosis
Efforts target disease‑modifying agents, neuroprotective strategies, and seizure control.
Immune‑Mediated & Inflammatory Diseases
The investigator engages in studies of systemic and organ‑specific immune disorders.
- Atopic Dermatitis
- Ulcerative Colitis
- Rheumatoid Arthritis
- Systemic Lupus Erythematosus
- Systemic Sclerosis
- Hidradenitis Suppurativa
- Idiopathic Pulmonary Fibrosis
- Extra‑pulmonary Sarcoidosis
- Alpha‑1 Antitrypsin Deficiency‑Associated Liver Disease
Research emphasizes biologic therapies, steroid‑sparing approaches, and disease‑activity biomarkers.
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