Grainne O.
- Country
- Ireland
- Department
- Medical Oncology
Research Overview
- Phase 1/2 Open‑Label Study of RAS(ON) Inhibitor RMC-6291 with ivonescimab ± combination therapy in patients with advanced RAS‑mutated solid tumors
- Efficacy and Safety Evaluation of Ifinatamab Deruxtecan in Recurrent or Metastatic Solid Tumors: A Phase 1b/2 Open-Label Study
- Phase 2/3 Randomized Study of BMS-986504 with Nab-Paclitaxel and Gemcitabine vs. Placebo in Metastatic Pancreatic Ductal Adenocarcinoma with Homozygous MTAP Deletion
Data & Insights
Has run more than one trial at 35 of 152 partner sites.
Specializations
Gastrointestinal Oncology
The investigator specializes in treating advanced gastrointestinal malignancies, focusing on hepatocellular carcinoma, colorectal cancer, and biliary tract cancer. Their research extends to innovative treatments for adenocarcinoma of the esophagus, gastroesophageal junction, and stomach cancers.
- Hepatobiliary Cancers
- Colorectal Malignancies
- Upper GI Tract Tumors
Gynecologic Oncology
The investigator demonstrates expertise in treating gynecologic cancers, particularly endometrial cancer, ovarian cancer, and cervical cancer. Their work encompasses treatment approaches for recurrent and metastatic manifestations of these conditions.
- Endometrial Malignancies
- Ovarian Neoplasms
- Cervical Tumors
Additional Oncology Focus
The investigator's expertise extends to head and neck squamous cell carcinoma, pancreatic ductal adenocarcinoma, and urothelial carcinoma. They also concentrate on breast cancer with specific attention to HER2 expression patterns and cutaneous melanoma.
- Head and Neck Cancer
- Pancreatic Cancer
- Breast Cancer Subtypes
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