Gilles K.
- Country
- France
- Department
- gynecology
Research Overview
- Effectiveness of a Molecular Biology Screen-and-Treat Strategy Using Metronidazole and Combination Therapy for Vaginal Flora Abnormalities in High-Risk Pregnancies
- Aspirin for the Prevention of Preeclampsia and Pregnancy outcomes in nulliparous women after Assisted Reproductive Technology. APPART trial
- Evaluation of Ceftriaxone Sodium, Clarithromycin, and Metronidazole in Reducing Neonatal Mortality in Threatened Late Miscarriage with Intact Membranes
Data & Insights
Has run more than one trial at 26 of 43 partner sites.
Specializations
Maternal-Fetal Medicine and Pregnancy Complications
Clinical research activity includes preterm birth, preterm premature rupture of membranes, preeclampsia, pregnancy-related hypertension, and postpartum anemia, with interest in obstetric care for high-risk pregnancies and perinatal outcomes.
- Chronic hypertension in pregnancy
- Preeclampsia prevention
- PPROM
- Perinatal morbidity and mortality
The therapeutic focus also extends to interventions used in obstetric emergencies and pregnancy-associated risk reduction.
Gynecologic Oncology and Women's Cancers
Research involvement covers ovarian cancer, endometrial cancer, cervical cancer, vulvar intraepithelial lesions, and advanced gastroesophageal and hepatobiliary malignancies relevant to gynecologic and abdominal oncology.
- Advanced ovarian cancer
- Endometrial carcinoma
- Cervical cancer
- Gynecologic metastatic disease
Therapeutic interests include systemic treatment strategies for recurrent, metastatic, and biomarker-defined tumors.
Autoimmune and Inflammatory Disease
Clinical trial activity includes systemic lupus erythematosus, lupus nephritis, Sjögren's disease, systemic sclerosis, vasculitis, and inflammatory bowel disease, reflecting a strong interest in immune-mediated disorders.
- Rheumatologic autoimmune disease
- Renal involvement in autoimmunity
- Inflammatory arthritis
- Uveitis and systemic inflammation
The therapeutic landscape also includes conditions requiring targeted immunomodulation across multiple organ systems.
Respiratory, Critical Care, and Infectious Diseases
Research participation spans asthma, chronic obstructive pulmonary disease, interstitial lung disease, pulmonary fibrosis, sepsis, and pneumonia, alongside viral and bacterial infections in hospitalized and intensive care settings.
- Severe asthma
- Fibrotic lung disease
- Sepsis and severe infection
- Hospital-acquired respiratory illness
Therapeutic interest includes management of acute respiratory deterioration and infection-related complications in vulnerable adults.
Hematology, Oncology, and Transplant-Related Care
Clinical research also involves acute leukemias, lymphomas, multiple myeloma, myelodysplastic syndromes, and stem cell transplantation, with additional attention to supportive care in complex hematologic disease.
- Leukemia and lymphoma
- Myeloid malignancies
- Hematopoietic stem cell transplantation
- Thrombocytopenia and coagulation disorders
The therapeutic emphasis includes advanced treatment options for relapsed or refractory blood cancers and transplant-associated complications.
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