Ghada S.
- Country
- France
- Department
- Réanimation
Research Overview
Data & Insights
Has run more than one trial at 0 of 12 partner sites.
Specializations
Critical Care and Septic Shock
Focuses on therapeutic strategies for patients experiencing severe circulatory failure and organ dysfunction in the intensive care environment.
- Adjunctive Dobutamine in septic cardiomyopathy
- High‑dose vitamin C in post‑cardiac arrest shock
- Nicotinamide supplementation for septic shock‑related kidney protection
Research conducted at Centre Hospitalier Bethune Beuvry.
Infectious Diseases and Antimicrobial Stewardship
Investigates optimal antimicrobial regimens for resistant bacterial infections in critically ill patients.
- Carbapenem‑sparing therapy for ESBL‑producing Enterobacteriaceae
- Oral rifabutin versus rifampicin for staphylococcal prosthetic joint infection
- Management of ESBL sepsis in the ICU
Emphasis on preserving antibiotic efficacy.
Oncology – Gastrointestinal and Head‑Neck Cancers
Targets systemic and locoregional treatments for gastrointestinal malignancies and head‑neck squamous cell carcinoma.
- FOLFOX combined with immunotherapy for gastric and oesophageal adenocarcinoma
- Adjuvant mFOLFIRINOX for ampullary adenocarcinoma
- Avelumab‑cetuximab radiotherapy for locally advanced head‑neck cancer
Trials integrate molecular biomarkers such as ctDNA.
Neurology and Pain Management
Explores pharmacologic interventions for seizure disorders and radicular pain.
- EQU‑001 as add‑on therapy for focal onset seizures
- Gabapentin versus placebo for acute lumbosacral radiculopathy
- Caffeine modulation of cognitive decline in early Alzheimer’s disease
Endpoints include seizure frequency and pain scores.
Cardiovascular and Renal Complications
Evaluates therapies addressing cardiac arrest sequelae and renal injury in acute care.
- Vitamin C to reduce vasopressor need after out‑of‑hospital cardiac arrest
- Apixaban versus warfarin in peritoneal dialysis patients with atrial fibrillation
- High‑dose vitamin B3 to prevent major adverse kidney events in septic shock
Studies monitor hemodynamic and renal biomarkers.
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