Gerardo G. G.
- Country
- Spain
- Department
- Neurology
Research Overview
- Efficacy and Safety of DYNE-101 in Participants with Myotonic Dystrophy Type 1: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study
- Evaluation of Gefurulimab (ALXN1720) Efficacy and Safety in Adults with Generalized Myasthenia Gravis: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study
- An Open-Label Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Efficacy, and Safety of a Single Dose of ANX005 in Participants With Guillain-Barré Syndrome
Data & Insights
Has run more than one trial at 16 of 71 partner sites.
Specializations
Neuromuscular and movement disorders
Clinical research activity includes therapies for early Parkinson’s disease, myotonic dystrophy type 1, and neurogenic orthostatic hypotension, with attention to symptomatic control and functional outcomes in progressive neurological disease.
- Early Parkinson’s disease
- Myotonic dystrophy type 1
- Neurogenic orthostatic hypotension
Work in this area also extends to treatments aimed at improving muscle function and reducing disease-related worsening in chronic neuromuscular conditions.
Autoimmune and neuroimmunology
The investigator is involved in studies of generalized myasthenia gravis, systemic lupus erythematosus, and ANCA-associated vasculitis, reflecting a strong therapeutic focus on immune-mediated disorders with neurological and systemic involvement.
- Generalized myasthenia gravis
- Systemic lupus erythematosus
- ANCA-associated vasculitis
Additional interest includes non-infectious uveitis and other inflammatory conditions requiring targeted immunomodulatory treatment.
Pain, allergy, and inflammatory dermatology
Research involvement covers diabetic peripheral neuropathic pain, atopic dermatitis, and allergic rhinoconjunctivitis, including pollen-driven respiratory and nasal allergy syndromes.
- Diabetic peripheral neuropathic pain
- Atopic dermatitis
- Allergic rhinoconjunctivitis
Therapeutic interests also include allergen-specific immunotherapy for grass and olive pollen sensitisation and related asthma symptoms.
Cardiovascular, thrombotic, and metabolic disease
Clinical trial activity spans hypercholesterolemia, hypertension, atherosclerotic cardiovascular disease, acute heart failure, and acute pulmonary embolism, with emphasis on risk reduction and acute care.
- Hypercholesterolemia
- Hypertension
- Acute pulmonary embolism
Related interests include obesity, overweight, osteoarthritis of the knee, and metabolic liver disease in HIV-infected people.
Oncology and hematologic malignancies
The investigator’s portfolio includes studies in acute myeloid leukemia, newly diagnosed multiple myeloma, metastatic castration-resistant prostate cancer, ovarian cancer, endometrial cancer, and non-muscle invasive bladder cancer.
- Acute myeloid leukemia
- Newly diagnosed multiple myeloma
- Ovarian cancer
Additional oncologic involvement includes HER2-positive breast cancer and other advanced solid tumors requiring novel systemic treatment strategies.
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