Gabriela R. M.
- Country
- Spain
- Department
- Hematology
Research Overview
- Pharmacokinetic, Safety, and Efficacy Evaluation of ASTX727 and Venetoclax in Adult Patients with Acute Myeloid Leukemia
- Phase 2/3 Randomized Open‑Label Study of MK‑1045 Versus Blinatumomab in Relapsed/Refractory CD19‑Positive B‑Cell Acute Lymphoblastic Leukemia
- Phase 2/3 Randomized Study of Pivekimab Sunirine Plus Venetoclax and Azacitidine in Adults with Newly Diagnosed AML Ineligible for Intensive Chemotherapy
Data & Insights
Has run more than one trial at 147 of 261 partner sites.
Specializations
Hematologic Malignancies
The investigator is involved in clinical research across a broad spectrum of blood cancers, with particular attention to acute myeloid leukemia, myelodysplastic syndromes, lymphoma, and multiple myeloma. Activity also includes studies in chronic lymphocytic leukemia, mantle cell lymphoma, and other relapsed or refractory hematologic neoplasms.
- Acute myeloid leukemia
- Myelodysplastic syndromes
- Diffuse large B-cell lymphoma
- Multiple myeloma
- Chronic lymphocytic leukemia
Research interests extend to cellular therapy, transplant-related complications, and treatment strategies for high-risk or relapsed/refractory hematologic disease.
Solid Tumors and Precision Oncology
Clinical trial involvement spans multiple solid tumors, especially breast cancer, non-small cell lung cancer, colorectal cancer, gastrointestinal cancers, and genitourinary malignancies. The portfolio also includes melanoma, pancreatic cancer, hepatocellular carcinoma, and urothelial carcinoma.
- Breast cancer
- Non-small cell lung cancer
- Colorectal cancer
- Hepatocellular carcinoma
- Urothelial carcinoma
The investigator is also engaged in molecularly defined cancer research, including tumors with HER2, EGFR, KRAS, ALK, and BRCA-related alterations.
Autoimmune, Inflammatory, and Immune-Mediated Disorders
Research activity includes autoimmune disease and immune-mediated inflammation, with studies in systemic lupus erythematosus, rheumatoid arthritis, psoriatic arthritis, multiple sclerosis, and inflammatory bowel disease. Additional work covers atopic dermatitis, psoriasis, hidradenitis suppurativa, and immune thrombocytopenia.
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Multiple sclerosis
- Ulcerative colitis
- Atopic dermatitis
There is also involvement in immune dysregulation conditions such as Sjögren’s syndrome, systemic sclerosis, and autoimmune cytopenias.
Hepatology and Metabolic Liver Disease
The investigator’s clinical research landscape includes liver disease and metabolic hepatology, with studies in hepatocellular carcinoma, primary biliary cholangitis, primary sclerosing cholangitis, nonalcoholic steatohepatitis, and cirrhosis. Work also extends to cholestatic pruritus and alcohol-related liver disease.
- Primary biliary cholangitis
- Nonalcoholic steatohepatitis
- Cirrhosis
- Hepatocellular carcinoma
- Cholestatic pruritus
Therapeutic interests also include liver fibrosis, hepatic inflammation, and complications linked to chronic hepatobiliary disorders.
Cardiovascular, Renal, and Respiratory Medicine
Clinical trial involvement covers cardiovascular disease, heart failure, atherosclerotic disease, and myocardial infarction, alongside chronic kidney disease and renal impairment. The respiratory portfolio includes asthma, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, and systemic sclerosis-associated interstitial lung disease.
- Heart failure
- Chronic kidney disease
- Atherosclerotic cardiovascular disease
- Chronic obstructive pulmonary disease
- Idiopathic pulmonary fibrosis
The investigator is also engaged in research on thromboembolic disease and cardiorenal risk, reflecting interest in overlapping organ-system disorders.
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