Fulvia F.
- Country
- Italy
- Department
- 2400:U.O.C. di Ematologia e Trapianto Emopoietico
Research Overview
Data & Insights
Has run more than one trial at 0 of 21 partner sites.
Specializations
Myeloid Neoplasms
Investigator concentrates on therapeutic strategies for Acute Myeloid Leukemia with molecular subtypes, including NPM1‑mutated disease and high‑risk presentations.
- Acute Myeloid Leukemia with NPM1 mutation
- Favorable‑intermediate‑risk Acute Myeloid Leukemia
- Acute Myeloid Leukemia
Emphasis on integrating novel agents with conventional chemotherapy and post‑remission maintenance.
Lymphoid Malignancies
Focus lies on curative and salvage approaches for Acute Lymphoblastic Leukemia, Diffuse Large B‑Cell Lymphoma, and Follicular Lymphoma.
- Adult Philadelphia Chromosome‑Positive Acute Lymphoblastic Leukemia
- Adult Philadelphia Chromosome‑Negative Acute Lymphoblastic Leukemia
- Diffuse Large B‑Cell Lymphoma ABC
- Elderly patients with Diffuse Large B‑Cell Lymphoma
- Follicular Lymphoma
- Hodgkin’s lymphoma
- Mantle Cell Lymphoma
Incorporates immunochemotherapy, targeted kinase inhibition, and transplant‑based consolidation.
Molecularly Targeted Solid Tumor Oncology
Research addresses Non‑Small Cell Lung Cancer, colorectal carcinoma, and breast cancer subtypes defined by actionable mutations such as KRAS G12C, EGFR, HER2, and ER/PR status.
- Advanced Non‑Small Cell Lung Cancer
- KRAS G12C‑mutated colorectal cancer
- EGFR‑mutated Non‑Small Cell Lung Cancer
- HER2‑positive metastatic breast cancer
- ER‑positive, HER2‑negative advanced breast cancer
- BRCA‑wild‑type advanced ovarian cancer
- High‑Risk Non‑muscle‑invasive Bladder Cancer
- Metastatic triple‑negative PD‑L1 positive breast cancer
Targets include tyrosine kinase inhibitors, CDK4/6 blockade, and checkpoint inhibition combined with chemotherapy.
Complement‑Mediated and Autoimmune Hematologic Disorders
Investigator explores treatments for rare complement‑driven diseases such as Paroxysmal Nocturnal Hemoglobinuria and transplant‑associated thrombotic microangiopathy, as well as immune‑mediated hemolysis.
- Paroxysmal Nocturnal Hemoglobinuria
- Hematopoietic stem cell transplant‑associated thrombotic microangiopathy
- Thrombotic Thrombocytopenic Purpura
- Warm autoimmune hemolytic anemia
- Immune‑mediated thrombotic thrombocytopenic purpura
Evaluates complement inhibitors and novel monoclonal antibodies to restore hematologic homeostasis.
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