Friedrich S.
- Country
- Germany
- Department
- Klinik für Innere Medizin II / Sektion für Stammzelltransplatation und zelluläre Immuntherapie
Research Overview
- Evaluation of Cardiac Safety of Treosulfan-Based Chemotherapy in Patients with Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
- A multi-center randomized, double blinded phase IIb trial evaluating oral pooled fecal microbiotherapy MaaT033 to prevent allogeneic hematopoietic cell transplantation complications
- Phase 3 Randomized Open-Label Study of Mesenchymal Stromal Cells MC0518 Versus Best Available Therapy in Steroid-Refractory Acute Graft-Versus-Host Disease
Data & Insights
Has run more than one trial at 48 of 120 partner sites.
Specializations
Stem Cell Transplantation Complications
The investigator specializes in managing complications following allogeneic hematopoietic stem cell transplantation, with particular emphasis on graft versus host disease treatment approaches.
- Steroid-refractory acute GvHD
- Chronic GvHD management
- Novel therapeutic interventions
Research includes evaluation of mesenchymal stromal cells and innovative oral medications for GvHD treatment.
Hematologic Malignancies
Focuses on treatment strategies for patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) requiring transplantation.
- Conditioning regimen optimization
- Transplant outcomes in AML/MDS
- Treatment protocols development
Investigates various conditioning approaches including treosulfan and melphalan-based treatments.
Transplant Innovation
Explores advanced approaches in hematopoietic cell transplantation, including novel preventive strategies and treatment methodologies.
- Microbiome-based interventions
- Immunosuppressive protocols
- Cardiac safety monitoring
Studies include evaluation of fecal microbiotherapy and optimization of post-transplant care protocols.
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