Frida Bugge A.
- Country
- Norway
- Department
- Oslo Myeloma Center
Research Overview
- Phase 3 Randomized Study of JNJ-79635322 Versus Teclistamab in Relapsed or Refractory Multiple Myeloma After Prior PI, IMiD, and Anti-CD38 Therapy
- Phase II Open‑Label Multicenter Study of Teclistamab + Pomalidomide in Relapsed/Refractory Multiple Myeloma after 1–3 Prior Lines including Lenalidomide and Anti‑CD38
- EFfIcacy and Tolerability of FIXed duration teclistamab and talquetamab FOR FRAIL patients with newly diagnosed multiple myeloma (2 cohort study) - the EMN 37 FITFIX FOR FRAIL trial
Data & Insights
Has run more than one trial at 10 of 74 partner sites.
Specializations
Hematologic Malignancies
Research emphasizes multiple myeloma and related plasma cell disorders, alongside acute leukemias and chronic leukemias and diverse lymphomas.
- Multiple myeloma
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- Chronic lymphocytic leukemia
- Diffuse large B‑cell lymphoma
Efforts target disease biology, treatment resistance, and outcomes in transplant‑eligible and refractory patient cohorts.
Cardiovascular and Metabolic Disorders
Investigations include atherosclerotic cardiovascular disease, aortic stenosis, and atrial rhythm abnormalities such as atrial fibrillation, as well as heart failure phenotypes.
- Atherosclerotic cardiovascular disease
- Aortic stenosis
- Atrial fibrillation
- Heart failure with preserved ejection fraction
- Hypertension
Focus lies on risk stratification, disease progression, and therapeutic optimization in adult populations.
Solid Tumor Oncology
Clinical work addresses major solid cancers including non‑small cell lung cancer, breast carcinoma, colorectal adenocarcinoma, and gastric cancer.
- Non‑small cell lung cancer
- Breast carcinoma
- Colorectal cancer
- Gastric cancer
- Melanoma
Studies explore molecular subtypes, targeted therapies, and outcomes across disease stages.
Neurological and Neurodegenerative Disorders
Research includes neurodegenerative conditions such as Alzheimer’s disease and amyotrophic lateral sclerosis, as well as primary headache disorders like migraine.
- Alzheimer’s disease
- Amyotrophic lateral sclerosis
- Migraine
- Multiple sclerosis
- Epilepsy
Efforts aim to delineate disease mechanisms and evaluate emerging therapeutic strategies.
Rare and Immune‑Mediated Conditions
Projects cover autoimmune and rare diseases such as systemic lupus erythematosus, primary sclerosing cholangitis, and hidradenitis suppurativa.
- Systemic lupus erythematosus
- Primary sclerosing cholangitis
- Hidradenitis suppurativa
- Idiopathic pulmonary fibrosis
- Graft‑versus‑host disease
Investigations prioritize disease activity monitoring and novel immunomodulatory approaches.
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