Frede D.
- Country
- Denmark
- Department
- N/A
Research Overview
Data & Insights
Has run more than one trial at 22 of 170 partner sites.
Specializations
Cardiovascular medicine
Clinical research in atherosclerotic cardiovascular disease, myocardial infarction, heart failure, atrial fibrillation, hypertension, and calcific aortic valve stenosis, with additional interest in lipid-related risk and vascular prevention.
- Major adverse cardiovascular events
- Lipoprotein(a) and lipid-lowering therapy
- Stroke prevention
- Mechanical valve anticoagulation
Also involved in studies addressing cardiovascular risk in type 1 diabetes and type 2 diabetes, as well as prevention strategies for people with established or high-risk vascular disease.
Kidney disease and metabolic disorders
Research activity includes chronic kidney disease, end-stage renal disease, diabetic kidney disease, and renal protection in patients with metabolic and cardiovascular comorbidity.
- Non-diabetic chronic kidney disease
- Renal progression
- Obesity and pre-diabetes
- Hypertriglyceridemia
Further therapeutic interest is seen in non-alcoholic steatohepatitis, liver cirrhosis, and cardiometabolic risk reduction in patients with overlapping renal and hepatic disease.
Neurology and immune-mediated disease
Clinical involvement extends to multiple sclerosis, including relapsing and progressive forms, as well as inflammatory conditions affecting the nervous system and joints.
- Migraine and medication overuse headache
- Polymyalgia rheumatica
- Giant cell arteritis
- Active psoriatic arthritis
Additional interest includes secondary osteoporosis and other immune-mediated disorders requiring long-term symptom control and disease stabilization.
Respiratory and ear, nose, and throat disease
Research spans chronic obstructive pulmonary disease, non-cystic fibrosis bronchiectasis, and chronic rhinosinusitis with nasal polyposis, reflecting a focus on chronic airway inflammation and symptom burden.
- COPD exacerbation prevention
- Upper airway inflammatory disease
- Biologic therapy
- Cardiopulmonary outcomes
Therapeutic interest also includes respiratory care in patients with complex cardiometabolic disease and obesity-related breathing disorders.
Gastroenterology, oncology, and acute care
Clinical trial involvement covers ulcerative colitis, Crohn's disease, breast cancer, diffuse large B-cell lymphoma, multiple myeloma, and chronic lymphocytic leukemia.
- Inflammatory bowel disease
- Metastatic and early breast cancer
- Hematologic malignancies
- Sepsis and critical illness
Additional work includes complicated urinary tract infections, cardiac arrest, and emergency treatment of shock, indicating engagement with acute and hospital-based therapeutic innovation.
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