Frank D. V.
- Country
- The Netherlands
- Department
- Infectious Disease
Research Overview
- Evaluation of Human Normal Immunoglobulin Dosing on Lung Disease Progression in Patients with Primary Antibody Deficiency
- Phase III Randomized Study of Olorofim Versus Liposomal Amphotericin B in Patients with Invasive Aspergillosis
- Evaluation of Long-term Safety and Tolerability of Human Normal Immunoglobulin and Hyaluronidase (Human Recombinant) in Primary Immunodeficiency Diseases
Data & Insights
Has run more than one trial at 31 of 116 partner sites.
Specializations
Inflammatory Bowel Disease and Gastrointestinal Immunology
Frank de Veerdonk is involved in clinical research on Crohn’s disease, ulcerative colitis, and broader inflammatory bowel disease programs, with attention to immune-mediated control of intestinal inflammation and symptom relief.
- Crohn’s disease
- Ulcerative colitis
- Immune-mediated intestinal inflammation
His trial portfolio also includes interest in refractory and complex gastrointestinal inflammatory conditions, including disease activity and remission-focused therapeutic development.
Renal and Glomerular Diseases
His research landscape includes IgA nephropathy, C3 glomerulopathy, immune-complex membranoproliferative glomerulonephritis, and other proteinuric glomerular diseases, reflecting a strong focus on kidney inflammation and renal preservation.
- IgA nephropathy
- C3 glomerulopathy
- Proteinuric kidney disease
Additional activity extends to chronic kidney disease, primary membranous nephropathy, focal segmental glomerulosclerosis, and transplant-related renal protection.
Infectious Diseases and Antimicrobial Therapy
As an investigator in Infectious Disease, he is engaged in studies addressing sepsis, Staphylococcus aureus bacteremia, tuberculosis, COVID-19, and invasive fungal disease, including aspergillosis and other mold infections.
- Sepsis
- Tuberculosis
- Invasive fungal infections
His work also spans respiratory and bloodstream infections, supporting therapeutic development in difficult-to-treat infectious syndromes.
Cardiovascular Medicine and Thrombotic Risk
His trial activity includes atherosclerotic cardiovascular disease, acute coronary syndrome, myocardial infarction, atrial fibrillation, heart failure, and hypertension, with emphasis on prevention and event reduction.
- Atherosclerotic cardiovascular disease
- Acute coronary syndrome
- Thromboembolic disease
He also contributes to research in venous thromboembolism, pulmonary embolism, and lipid-related cardiovascular risk, including elevated lipoprotein(a).
Autoimmune, Oncology, and Neurologic Disorders
His broader clinical research includes systemic sclerosis, rheumatoid arthritis, lupus, and psoriatic arthritis, alongside oncology programs in urothelial cancer, non-small cell lung cancer, colorectal cancer, and lymphoma.
- Systemic autoimmune disease
- Solid tumors
- B-cell malignancies
He is also involved in studies of Parkinson’s disease, retinitis pigmentosa, and other immune- and neurodegenerative conditions.
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