Françoise K. B.
- Country
- France
- Department
- 1206: Medecine Nucléaire
Research Overview
- Phase I/II Evaluation of 177Lu-PentixaTher Radioligand Therapy in Relapsed/Refractory CXCR4-Positive Acute Leukemia
- Phase I/II Study of [225Ac]Ac-PSMA-R2 in Metastatic Hormone-Sensitive and Castration-Resistant Prostate Cancer with/without Prior 177Lu-PSMA Therapy
- A pivotal phase 3 clinical trial to assess the diagnostic performance and safety of [68Ga]Ga-PentixaFor ([68Ga]Ga-PTF), a positron emission tomography (PET) imaging agent, versus [18F]FDG PET/CT imaging, for staging of patients with confirmed marginal zone lymphoma (MZL) exemplary for CXCR4-positive malignant lymphomas: a prospective, international, multi-center, comparative, randomized, cross-over, open-label lymphoma diagnostic trial (LYMFOR).
Data & Insights
Has run more than one trial at 7 of 31 partner sites.
Specializations
Nuclear Medicine Imaging
The investigator specializes in advanced PET/CT imaging techniques, particularly focusing on novel radiotracers for cancer detection. Their work includes evaluating [68Ga]Ga-PentixaFor imaging for lymphoma staging and [68Ga]Ga-DPI-4452 for solid tumor assessment.
- Diagnostic imaging for lymphoma
- Solid tumor visualization
- Radiotracer development
Their expertise extends to comparative imaging studies evaluating novel tracers against conventional methods.
Therapeutic Nuclear Medicine
The investigator conducts research in radioligand therapy, with particular expertise in treating various oncological conditions. Their work encompasses both hormone-sensitive and castration-resistant prostate cancer treatments using targeted radiopharmaceuticals.
- Prostate cancer therapy
- Leukemia treatment
- Novel radiopharmaceuticals
Their research includes applications of both alpha and beta-emitting radioisotopes for cancer treatment.
Oncology Focus Areas
The investigator's research spans multiple oncological conditions, including both hematological malignancies and solid tumors. Their expertise covers metastatic disease and advanced cancer treatments.
- Marginal zone lymphoma
- Advanced solid tumors
- Acute leukemia
Their work addresses unresectable and metastatic cancers across multiple organ systems.
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