François D.
- Country
- France
- Department
- Neuro-oncology
Research Overview
- Dose-Escalation Study of [177Lu]Lu-DOTA-TATE with Standard Care in Newly Diagnosed Glioblastoma and as Monotherapy in Recurrent Glioblastoma.
- Evaluation of Safety and Efficacy of L19TNF and Lomustine in Patients with Glioblastoma at First Progression
- Evaluation of Temozolomide Monotherapy in Adult Patients with Non-Enhancing Diffuse Brainstem Gliomas Exhibiting Infiltrative Progression
Data & Insights
Has run more than one trial at 84 of 176 partner sites.
Specializations
Primary Brain Tumors
The investigator specializes in treating various types of gliomas, with particular emphasis on glioblastoma management. Their work encompasses both newly diagnosed cases and recurrent disease states.
- IDH-mutant Gliomas
- Diffuse Midline Gliomas
- Adult Brainstem Gliomas
Their expertise extends to specialized treatment approaches for MGMT unmethylated glioblastoma and various molecular subtypes.
Treatment Innovations
The investigator focuses on developing innovative therapeutic strategies including blood-brain barrier modulation and novel drug combinations for brain tumor treatment.
- Tumor Treating Fields Technology
- Ultrasound-induced BBB Opening
- Targeted Radiotherapy Approaches
Their work includes evaluation of combination therapies with established treatments like temozolomide.
Specialized Therapeutics
The investigator works with advanced therapeutic approaches including antibody-cytokine fusion proteins and novel targeted agents for brain tumors.
- Radionuclide Therapy
- Targeted Molecular Therapies
- Immunotherapy Applications
Their research includes assessment of meningioma treatments and novel therapeutic strategies for recurrent disease.
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