Francisco de Borja G. C. P.
- Country
- Spain
- Department
- Pneumology
Research Overview
- Long-term safety and efficacy of subcutaneous lunsekimig in adults with asthma: An open-label extension study
- Efficacy and Safety of Early Depemokimab Initiation as Add-on Therapy in Patients with Chronic Obstructive Pulmonary Disease and Type 2 Inflammation
- Phase 2b/3 Randomized Double‑Blind Placebo‑Controlled Trial of Lunsekimig in Adults with Inadequately Controlled Eosinophilic COPD
Data & Insights
Has run more than one trial at 271 of 628 partner sites.
Specializations
Breast Cancer and Endocrine Oncology
Clinical activity centers on ER-positive, HER2-negative, and HER2-positive breast cancer, including early-stage, locally advanced, metastatic, and high-risk disease. The investigator is also involved in studies addressing triple-negative breast cancer, PIK3CA-mutated disease, and treatment resistance in advanced breast cancer.
- Hormone receptor-driven breast cancer
- HER2-targeted therapy
- Triple-negative breast cancer
- Metastatic breast cancer
Research interest extends to adjuvant endocrine therapy, neoadjuvant treatment, and biomarker-defined breast cancer populations.
Haematologic Malignancies
The investigator contributes to trials in acute myeloid leukemia, acute lymphoblastic leukemia, multiple myeloma, and diverse lymphomas. Work also includes relapsed or refractory disease, transplant-related settings, and pediatric hematologic cancers.
- Acute myeloid leukemia
- Acute lymphoblastic leukemia
- Multiple myeloma
- B-cell lymphoma
Additional involvement includes myelodysplastic syndromes, myelofibrosis, and light chain amyloidosis.
Thoracic and Solid Tumor Oncology
Research activity includes non-small cell lung cancer, small cell lung cancer, renal cell carcinoma, ovarian cancer, endometrial cancer, and prostate cancer. The portfolio also covers head and neck cancer, colorectal cancer, urothelial cancer, and selected rare solid tumors.
- Non-small cell lung cancer
- Renal cell carcinoma
- Ovarian and endometrial cancer
- Prostate cancer
Interest also includes targeted therapy and immuno-oncology approaches across advanced solid tumors.
Respiratory, Inflammatory, and Cardiovascular Disease
The investigator is involved in studies of asthma, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, pulmonary arterial hypertension, and systemic sclerosis-associated interstitial lung disease. Cardiovascular research includes atherosclerotic cardiovascular disease, stroke, and coronary artery disease.
- Asthma and eosinophilic airway disease
- Chronic obstructive pulmonary disease
- Interstitial lung disease
- Stroke and vascular disease
Therapeutic focus also includes inflammatory skin disease and systemic immune-mediated conditions.
Infectious Disease, Metabolic, and Neurologic Disorders
Clinical interests extend to HIV infection, hepatitis B, latent tuberculosis infection, and selected bacterial infections. Additional work covers diabetes, obesity, metabolic dysfunction-associated steatotic liver disease, chronic kidney disease, and neurologic conditions such as stroke, multiple sclerosis, and glioblastoma.
- HIV and viral infection
- Latent tuberculosis infection
- Metabolic disease
- Neurologic disease
Research also includes immune thrombocytopenia, nephropathy, and other chronic multisystem disorders.
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