Francis A. A.
- Country
- Germany
- Department
- Klinik und Poliklinik für Stammzelltransplantation
Research Overview
- Evaluation of MB-CART2019.1 in Patients with Refractory Multiple Sclerosis: A Clinical Trial
- Long-Term Safety Evaluation of KYV-101 in Patients with Lupus Nephritis, Systemic Sclerosis, Myasthenia Gravis, Rheumatoid Arthritis, or Stiff Person Syndrome
- Early treatment intensification in patients with high risk Mantle Cell Lymphoma using CAR-T-cell treatment after an abbreviated induction therapy with Rituximab and Ibrutinib and 6 months Ibrutinib maintenance (Arm A) as compared to standard of care induction and maintenance (Arm B)
Data & Insights
Has run more than one trial at 69 of 145 partner sites.
Specializations
Hematopoietic Stem Cell Transplantation and Hematologic Malignancies
Advances the use of stem cell transplantation for curative intent in blood‑derived cancers and transplant‑related complications.
- Acute Myeloid Leukemia
- Acute Lymphoblastic Leukemia
- Chronic Myeloid Leukemia
- Myelodysplastic Syndromes
- Graft‑versus‑Host Disease
Combines cellular therapy with disease‑specific conditioning regimens to enhance remission durability.
Cardiovascular and Cerebrovascular Disease Management
Targets acute and chronic heart conditions, emphasizing innovative strategies for myocardial and cerebral protection.
- Acute Coronary Syndrome
- Acute Ischemic Stroke
- Heart Failure with Reduced Ejection Fraction
- Atrial Fibrillation
- Atherosclerotic Cardiovascular Disease
Integrates anti‑inflammatory and anti‑thrombotic approaches to lower major adverse cardiovascular events.
Solid Tumor Oncology
Focuses on therapeutic development for a broad spectrum of solid cancers, including targeted and immunologic modalities.
- Non‑Small Cell Lung Cancer
- Advanced Hepatocellular Carcinoma
- Metastatic Breast Cancer
- Pancreatic Ductal Adenocarcinoma
- Renal Cell Carcinoma
Prioritizes precision medicine based on molecular alterations and tumor microenvironment modulation.
Autoimmune and Inflammatory Disorders
Investigates immune‑modulating interventions for systemic and organ‑specific autoimmune conditions.
- Systemic Lupus Erythematosus
- Inflammatory Myopathy
- Hidradenitis Suppurativa
- Ulcerative Colitis
- Atopic Dermatitis
Emphasizes cytokine inhibition and cellular therapies to achieve durable remission.
Metabolic, Genetic and Rare Diseases
Addresses therapeutic gaps in inherited and metabolic disorders through novel biologic and gene‑based strategies.
- Fabry Disease
- Alport Syndrome
- Phenylketonuria
- Glycogen Storage Disease Type Ia
- VEXAS Syndrome
Leverages enzyme replacement, substrate reduction, and targeted molecular correction to improve patient outcomes.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.